0000000000190800

AUTHOR

Päivi Piirilä

showing 3 related works from this author

Associations between sports participation, cardiorespiratory fitness, and adiposity in young adult twins.

2011

Exercise behavior, cardiorespiratory fitness, and obesity are strongly influenced by genetic factors. By studying young adult twins, we examined to what extent these interrelated traits have shared genetic and environmental etiologies. We studied 304 twin individuals selected from the population-based FinnTwin16 study. Physical activity was assessed with the Baecke questionnaire, yielding three indexes: sport index, leisure-time index, and work index. In this study, we focused on sport index, which describes sports participation. Body composition was determined using dual-energy X-ray absorptiometry and cardiorespiratory fitness using a bicycle ergometer exercise test with gas exchange ana…

GerontologyAdultPhysiologyPhysical fitnessStatistics as TopicTwins030209 endocrinology & metabolismPhysical exerciseMotor Activity03 medical and health sciencesYoung Adult0302 clinical medicinePhysiology (medical)medicineBody SizeHumansYoung adultFinlandGenetic Association StudiesAdiposity2. Zero hungerbusiness.industryVO2 maxCardiorespiratory fitnessHeart030229 sport sciencesmedicine.diseaseTwin studyObesityGenetic epidemiologyPhysical FitnessFemalePsychologybusinessSportsJournal of applied physiology (Bethesda, Md. : 1985)
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Telomere Length in Circulating Leukocytes is Associated with Lung Function and Disease

2014

Several clinical studies suggest the involvement of premature ageing processes in chronic obstructive pulmonary disease (COPD). Using an epidemiological approach, we studied whether accelerated ageing indicated by telomere length, a marker of biological age, is associated with COPD and asthma, and whether intrinsic age-related processes contribute to the interindividual variability of lung function. Our meta-analysis of 14 studies included 934 COPD cases with 15 846 controls defined according to the Global Lungs Initiative (GLI) criteria (or 1189 COPD cases according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria), 2834 asthma cases with 28 195 controls, and s…

Lung DiseasesMalePulmonary and Respiratory MedicineSpirometryNetherlands Twin Register (NTR)Vital capacityVital Capacityennenaikainen vanheneminenDiseaseCohort StudiesPathogenesisPulmonary Disease Chronic ObstructiveTelomere HomeostasisSDG 3 - Good Health and Well-beingForced Expiratory VolumeastmaLeukocytes/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_HumansCOPDMedicinekeuhkoahtaumatautiAgedAsthmatelomeeriCOPDmedicine.diagnostic_testpremature agingbusiness.industrySmokingCase-control studyta3141Middle AgedTelomerespirometriamedicine.diseaseAsthmabiologinen ikäbiological age3. Good healthrespiratory tract diseasesEuropeSpirometryCase-Control StudiesImmunologyRegression Analysis/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalebusinessEuropean Respiratory Journal
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Pulmonary embolism location is associated with the co-existence of the deep venous thrombosis.

2019

Multiple studies have shown that in approximately half of individuals with pulmonary embolism (PE), the deep venous thrombosis (DVT) is not evident at the moment of PE diagnosis. The underlying factors and the origin of PE in these patients are not completely understood: missed DVT, embolization of DVT in its entirety, or de-novo PE being possible explanations. The aim of this study was to evaluate the differences in PE patient with or without co-existing DVT. Sixty-three consecutive PE patients were included. Whole leg bilateral Doppler compression ultrasound was performed to all patients. The PE location and extension, C-reactive protein, platelet count, hemostatic markers FV, FVIII, FXII…

AdultMalemedicine.medical_specialtyVEIN THROMBOSISmedicine.medical_treatment030204 cardiovascular system & hematologyFibrinogenPulmonary function testing03 medical and health sciencesTHROMBOEMBOLISM0302 clinical medicineInternal medicineSCOREmedicineFactor V LeidenFACTOR-V-LEIDENHumanscardiovascular diseasesEmbolizationProspective Studiescoagulationhemostatic markersProspective cohort studydeep venous thrombosisAgedRISKVenous ThrombosisHemostasisLegbusiness.industryUltrasonography DopplerHematologyGeneral MedicineNITRIC-OXIDE MEASUREMENTSMiddle Agedmedicine.disease3. Good healthPulmonary embolismVenous thrombosis3121 General medicine internal medicine and other clinical medicineHemostasisisolated pulmonary embolismCardiologyFemalebusinessPulmonary Embolism030215 immunologymedicine.drugBlood coagulationfibrinolysis : an international journal in haemostasis and thrombosis
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