Adherence to growth hormone (GH) therapy in naïve to treatment GH-deficient children: data of the Italian Cohort from the Easypod Connect Observational Study (ECOS)

Background: With the use of non-objective measurement, adherence to growth hormone (GH) therapy has been reported suboptimal in a large proportion of patients, and poor adherence has been shown to affect short-term growth response in patients receiving GH treatment. Objective: The Easypod™ electronic device allows objective measurement of adherence. In this study, we report 3-year prospective adherence data of the Italian cohort of naïve GH deficient (GHD) children extrapolated from the Easypod Connect Observational Study (ECOS) database. Patients and methods: Seventy-three GHD children naïve to GH treatment were included in the analysis. 22 Italian centers participated in the study. Result…

Irrigation strategies for optimal use of saline water in Mediterranean agriculture.

Salinization, land degradation and management of irrigation in arid and semi-arid countries.

Evaluation of Oil Flaxseed (Linum usitatissimum L.) Cultivar in Two Sowing Times and Two Locations of Southern Italy.

Multiple hormonal and metabolic deficiency syndrome in chronic heart failure: rationale, design, and demographic characteristics of the T.O.S.CA. Registry.

Recent evidence supports the concept that progression of chronic heart failure (CHF) depends upon an imbalance of catabolic forces over the anabolic drive. In this regard, multiple hormonal deficiency syndrome (MHDS) significantly has impacts upon CHF progression, and is associated with a worse clinical status and increased mortality. The T.O.S.CA. (Trattamento Ormonale nello Scompenso CArdiaco; Hormone Therapy in Heart Failure) Registry (clinicaltrial.gov = NCT02335801) tests the hypothesis that anabolic deficiencies reduce survival in a large population of mild-to-moderate CHF patients. The T.O.S.CA. Registry is a prospective multicenter observational study coordinated by “Federico II” Un…

The prognostic value of thyroid function tests in predominantly non-alcoholic cirrhotic patients: A prospective investigation

The prognostic value of thyroid function parameters (T3, T4, rT3 and the rT3: T3 ratio) and common liver tests (serum bilirubin, albumin and prothrombin activity) was investigated on hospital admission in 100 consecutive patients with predominantly non-alcoholic liver cirrhosis. Twenty-nine out of 100 patients had a well compensated cirrhosis and their mean values of thyroid tests were similar to those of 40 healthy controls. A low T3 syndrome was found in the remaining 71 decompensated patients. In these thyroid function parameters were correlated with serum bilirubin and prothrombin activity. Moreover mean values of all thyroid and liver tests, except serum albumin, were significantly dif…

Scenari di gestione dell’irrigazione con acque saline in un vigneto irriguo siciliano.

Management scenarios preventing salinization under irrigation with saline water.

Management scenarios aimed at optimizing irrigation in a Sicilian vineyard characterized by a cracking clay soil irrigated with saline water were explored for seven soil profiles (Baglio 1-Baglio 7), by using the simulation model soil-water-atmosphere-plant environment (SWAP), which accounts for shrinkage and cracking. Accurate prediction of water content, theta, was obtained for the seven profiles by expressing the soil hydraulic properties according to the Brutsaert retention equation coupled with the hydraulic conductivity model proposed by Gardner (B-G model). A satisfactory prediction of the electrical conductivity of saturated extract (ECsat) ad was obtained using for the dispersivity…