0000000000199567
AUTHOR
Sabine N. J. Jespers
Additional file 1 of Safety and efficacy of a probiotic-containing infant formula supplemented with 2���-fucosyllactose: a double-blind randomized controlled trial
Additional file 1.
Additional file 2 of Safety and efficacy of a probiotic-containing infant formula supplemented with 2���-fucosyllactose: a double-blind randomized controlled trial
Additional file 2.
Safety and efficacy of a probiotic-containing infant formula supplemented with 2'-fucosyllactose: a double-blind randomized controlled trial
Abstract Background Human milk oligosaccharides (HMOs) have important and diverse biological functions in early life. This study tested the safety and efficacy of a starter infant formula containing Limosilactobacillus (L.) reuteri DSM 17938 and supplemented with 2’-fucosyllactose (2’FL). Methods Healthy infants < 14 days old (n = 289) were randomly assigned to a bovine milk-based formula containing L. reuteri DSM 17938 at 1 × 107 CFU/g (control group; CG) or the same formula with added 1.0 g/L 2’FL (experimental group; EG) until 6 months of age. A non-randomized breastfed group served as reference (BF; n = 60). The primary endpoint was weight gain through 4 months of age in the formula-…