0000000000201803
AUTHOR
V Bellia
Predictors of serious adverse events and non-response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid
Background & Aims Obeticholic acid (OCA) has recently been restricted in patients with primary biliary cholangitis (PBC) with "advanced cirrhosis" because of its narrow therapeutic index. We aimed to better define the predicting factors of hepatic serious adverse events (SAEs) and non-response in cirrhotic patients undergoing OCA therapy. Methods Safety and efficacy of treatment were evaluated in a cohort of consecutive PBC cirrhotic patients started with OCA. OCA response was evaluated according to the Poise criteria. Risk factors for hepatic SAEs and non-response were reported as risk ratios (RR) with 95% confidence intervals (CIs). Results One hundred PBC cirrhotics were included, 97…
CT densitometry-based differential diagnosis between emphysematous and non-emphysematous lungs in elderly patients.
Purpose Methods and Materials Results Conclusion References Personal Information
Higher blood eosinophil levels after omalizumab treatment may be associated with poorer asthma outcomes
• Efficacy of school prevention programs in rising tobacco awareness in adolescents;
• Efficacy of school prevention programs in rising tobacco awareness in adolescents;
Il polmone nell' età senile
Valori di densità TC nella diagnosi differenziale tra polmone senile ed enfisema
Assessment of large and small airways wall thickness by HRCT in asthma
Purpose Methods and Materials Results Conclusion References Personal Information