0000000000202189

AUTHOR

Bruno Cardey

showing 3 related works from this author

Negative Impact of Citral on Susceptibility of Pseudomonas aeruginosa to Antibiotics

2021

Essential oils (EOs) or their components are widely used by inhalation or nebulization to fight mild respiratory bacterial infections. However, their interaction with antibiotics is poorly known. In this study we evaluated the effects of citral, the main component of lemongrass oil, on in vitro susceptibility of Pseudomonas aeruginosa to antibiotics. Exposure of strain PA14 to subinhibitory concentrations of citral increased expression of operons encoding the multidrug efflux systems MexEF-OprN and MexXY/OprM, and bacterial resistance to anti-pseudomonal antibiotics including imipenem (twofold), gentamicin (eightfold), tobramycin (eightfold), ciprofloxacin (twofold), and colistin (≥128-fold…

0301 basic medicineMicrobiology (medical)antibiotic resistancemedicine.drug_class[SDV]Life Sciences [q-bio]030106 microbiologyAntibioticsmedicine.disease_causeCitralMicrobiologyMicrobiology03 medical and health scienceschemistry.chemical_compoundtobramycin-citral Schiff baseTobramycinmedicine[CHIM]Chemical Sciencesessential oilscitralOriginal ResearchPseudomonas aeruginosaChemistryAminoglycosidecolistin-citral Schiff baseSciences du Vivant [q-bio]/Microbiologie et Parasitologie[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyeffluxQR1-5023. Good health030104 developmental biology[SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyPseudomonas aeruginosaColistin[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyGentamicinEfflux[SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriologymedicine.drugFrontiers in Microbiology
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Squalene versus cholesterol: Which is the best nanocarrier for the delivery to cells of the anticancer drug gemcitabine?

2018

Comptes Rendus Chimie - In Press.Proof corrected by the author Available online since jeudi 22 mars 2018

0301 basic medicineCholesterolGeneral Chemical Engineering02 engineering and technologyGeneral ChemistryPharmacology021001 nanoscience & nanotechnologyAnticancer drugGemcitabine3. Good health03 medical and health sciencesSqualenechemistry.chemical_compound030104 developmental biologychemistrymedicine[CHIM]Chemical SciencesNanocarriers0210 nano-technologyComputingMilieux_MISCELLANEOUSmedicine.drug
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Adsorption of water in Na-LTA zeolites: an ab initio molecular dynamics investigation

2021

The very wide range of applications of LTA zeolites, including the storage of tritiated water, implies that a detailed and accurate atomic-scale description of the adsorption processes taking place in their structure is crucial. To unravel with an unprecedented accuracy the mechanisms behind the water filling in NaA, we have conducted a systematic ab initio molecular dynamics investigation. Two LTA structural models, the conventional Z4A and the reduced one ZK4, have been used for static and dynamic ab initio calculations, respectively. After assessing this reduced model with comparative static DFT calculations, we start the filling of the α and β cages by water, molecule by molecule. This …

Range (particle radiation)Tritiated waterChemistryCationic polymerizationGeneral Physics and Astronomy02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnologyRing (chemistry)01 natural sciences0104 chemical sciences[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistrychemistry.chemical_compound[CHIM.POLY]Chemical Sciences/PolymersAdsorption[CHIM.ANAL]Chemical Sciences/Analytical chemistryChemical physicsAb initio quantum chemistry methodsMolecule[PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph]Physical and Theoretical Chemistry0210 nano-technologyZeolite[CHIM.RADIO]Chemical Sciences/RadiochemistryPhysical Chemistry Chemical Physics
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