Author: Lāsma Grīnberga

0000000000203312

AUTHOR

Lāsma Grīnberga

showing 2 related works from this author

Biofilmu veidojošo Staphylococcus epidermidis antibakteriālās rezistences un mecA gēna noteikšana

2017

Staphylococcus epidermidis baktērijas mūsdienās ir kļuvušas par visbiežāk izolētajiem un būtiskākajiem koagulāzes negatīvo stafilokoku pārstāvjiem nozokomiālajā vidē, jo, būdami dominējošie oportūnistiskie patogēni, tās izraisa ievērojamu skaitu ar medicīniskajām ierīcēm saistītu infekcijas slimību cilvēkiem ar novājinātu imūnsistēmu, kļūstot par nopietnu draudu sabiedrības veselībai. S. epidermidis patogenitāte izpaužas šo baktēriju spējā producēt biofilmas, kuras kalpo kā daudzfunkcionāls virulences un antibakteriālās rezistences faktors un padara šo patogēnu izraisītās slimības ļoti grūti ārstējamas, jo tiek atvieglota antibiotiku rezistences gēnu, tai skaitā SCCmec lokalizētā mecA gēna,…

antibakteriālā rezistencemecA gēnsStaphylococcus epidermidisbiofilmasFarmācijaDDT

researchProduct

No perifēro vēnu katetru uzsējumiem izdalīto Staphylococcus epidermidis bioplēvju veidošana un jutība pret antibakteriālajiem līdzekļiem

2015

Mūsdienās Staphylococcus epidermidis ir vieni no visbiežāk izolētajiem nozokomiālo infekciju izraisītājiem pacientu grupā ar tādiem riska faktoriem kā novājināta imūnsistēma un implantētām medicīniskajām ierīcēm. Visbūtiskākā ar svešķermeņiem saistīto infekciju patoģenēzē ir šo mikroorganismu spēja kolonizēt medicīnisko ierīču abiotiskās virsmas, formējot bioplēvi, kas sastāv no daudzslāņu šūnu klasteriem, iekļautiem ekstracelulārajā gļotu substancē un ir saistīta ar šo baktēriju rezistenci pret antibakteriālajiem līdzekļiem, padarot to izraisītās slimības grūti ārstējamas. Pētījuma mērķis: Analizēt no perifēro vēnu katetru uzsējumiem izdalīto Staphylococcus epidermidis bioplēvju veidošanas…

Staphylococcus epidermidisnozokomiālās infekcijasbioplēvesoportūnistiskais patogēnsFarmācijajutība pret antibakteriālajiem līdzekļiem

researchProduct

PEPhysical Sciences and Engineering
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LSLife Sciences
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