SKELETAL-MUSCLE METABOLISM IN THE LEG DURING EXERCISE IN PATIENTS WITH CONGESTIVE HEART-FAILURE

International audience

HIGH-FIELD MAGNETIC-RESONANCE-IMAGING (MRI) OF THE RABBIT KNEE

International audience

Nuclear magnetic resonance spectroscopy of phosphorus in Becker's dystrophy

P-31 NMR-SPECTROSCOPY IN MYOTONIC-DYSTROPHY

International audience

Growth hormone potentiates thyroid hormone effects on post-exercise phosphocreatine recovery in skeletal muscle.

International audience; OBJECTIVE: The aim of the study was to determine the respective impact of thyroxine and growth hormone on in vivo skeletal mitochondrial function assessed via post exercise phosphocreatine recovery. DESIGN: The hind leg muscles of 32 hypophysectomized rats were investigated using (31)P nuclear magnetic resonance spectroscopy at rest and during the recovery period following a non tetanic stimulation of the sciatic nerve. Each rat was supplemented with hydrocortisone and was randomly assigned to one of the 4 groups: the group Hx was maintained in hypopituitarism., the group HxT was treated with 1 μg/100g/day of thyroxine (T4), the group HxG with 0.2 IU/kg/day of recomb…

LEFT-VENTRICULAR CONTRACILITY AFTER HYPOTHERMIC PRESERVATION - PREDICTIVE VALUE OF P-31 - NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY

International audience; Abstract: Early graft failure accounts for a substantial portion of the mortality after heart transplantation. This factor underscores the need for the development of reliable methods for predicting graft performance and thus ensuring optimal clinical outcome. The aim of this study was to describe the link between myocardial metabolism evaluated throughout preservation with the use of phosphorus 31-nuclear magnetic resonance spectroscopy and ventricular contractility after reperfusion. Thirteen pig hearts were excised and preserved from 3 to 12 hours with clinical techniques. During preservation the hearts underwent, phosphorus 31-nuclear magnetic resonance spectrosc…