0000000000208639

AUTHOR

Matteo Cioni

0000-0002-7594-6939

showing 2 related works from this author

Therapeutic Perspectives in Psychoneuroendocrinimmunology(PNEI): Potential Role of Phosphatidylserine in Neuroendocrine-Immune Communications

1990

(1990). Therapeutic Perspectives in Psychoneuroendocrinimmunology(PNEI): Potential Role of Phosphatidylserine in Neuroendocrine-Immune Communications. International Journal of Neuroscience: Vol. 51, No. 3-4, pp. 299-301.

MaleAgingHypothalamo-Hypophyseal SystemGonadotropin RHbusiness.industryGeneral NeurosciencePhosphatidylserinesGeneral MedicinePhosphatidylserineInterleukine 2RatsAntibody productionchemistry.chemical_compoundImmune systemchemistryMemoryImmunologyAnimalsLearningMedicineFemaleProestrusbusinessNeuroscienceReceptors LHRHInternational Journal of Neuroscience
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Phosphatidylserine counteracts physiological and pharmacological suppression of humoral immune response

1990

Phosphatidylserine (PS) is a necessary cofactor for protein kinase C (PKC) activation, and changes in the synthesis of PS have been shown to participate in the mechanism(s) involved in the transmembrane signaling of interleukin 1 (IL-1). In view of the age-associated defects in T-cell functions, in the present study we have addressed the question of whether an in vivo treatment with PS might interfere with such processes. Furthermore, the effect of an in vitro treatment with PS in human peripheral blood monocytes (PBMC) or splenocytes activated with a lectin mitogen, on the expression of IL-2 receptor, was assessed. While the process of ageing was accompanied by a marked decline of humoral …

Agingmedicine.medical_specialtyReceptor expressionPhosphatidylserinesIn Vitro Techniqueschemistry.chemical_compoundImmune systemInternal medicineImmune TolerancemedicineAnimalsHumansReceptorProtein Kinase CProtein kinase CPharmacologybiologyInterleukinRats Inbred StrainsReceptors Interleukin-2PhosphatidylserineRatsEndocrinologychemistryHumoral immunityLeukocytes Mononuclearbiology.proteinFemaleAntibodySpleenImmunopharmacology
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