0000000000210013
AUTHOR
Guillaume Charbonnier
Safety and Outcome of Revascularization Treatment in Patients With Acute Ischemic Stroke and COVID-19: The Global COVID-19 Stroke Registry.
Background and ObjectivesCOVID-19–related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19.MethodsThis was a retrospective multicenter cohort study of consecutive patients with AIS receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 and June 2021 tested for severe acute respiratory syndrome coronavirus 2 infection. With a doubly robust model combining propensity score weighting and multivariate regress…
A global palaeoclimatic reconstruction for the Valanginian based on clay mineralogical and geochemical data
International audience; High-resolution clay mineral and δ18Ocarb analyses have been performed on three sections of Valanginian age (Early Cretaceous), from northwestern (~20–30°N) and southern (~53°S) Tethyan realms. The data have been integrated in a large set of published mineralogical (clays), and geochemical (δ18Ocarb, δ18Obivalve, δ18Olenticulina, δ18Obelemnite, and TEX86) data from 17 sections, situated between ~45°N and ~53°S. Based on this data set, we provide new insights into Valanginian climate conditions from a wide range of palaeolatitudes. We highlight climate trends within specific areas and identify main climate belts. In the Proto-North Atlantic realm (~15–17°N) large amou…