0000000000211145

AUTHOR

Gonzalez-gay M. A.

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Clinical spectrum time course in anti jo-1 positive antisynthetase syndrome: Results from an international retrospective multicenter study

2015

Anti Jo-1 antibodies are the main markers of the antisynthetase syndrome (ASSD), an autoimmune disease clinically characterized by the occurrence of arthritis, myositis, and interstitial lung disease (ILD). These manifestations usually co-occur (for practical purpose complete forms) in the same patient, but cases with only 1 or 2 of these findings (for practical purpose incomplete forms) have been described. In incomplete forms, the ex novo occurrence of further manifestations is possible, although with frequencies and timing not still defined. The aim of this international, multicenter, retrospective study was to characterize the clinical time course of anti Jo-1 positive ASSD in a large c…

MalePathologyNeurologyAnti Jo-1:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective Studies [Medical Subject Headings]MedizinArthritisAntisynthetase syndrome:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]AntinuclearMasculinoMyositis:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]Medicine (all)Interstitial lung diseaseFemeninoGeneral MedicineMiddle Aged:Diseases::Musculoskeletal Diseases::Muscular Diseases::Myositis [Medical Subject Headings]HumanosAnticuerpos antinuclearesAntibodies Antinuclear:Diseases::Musculoskeletal Diseases::Joint Diseases::Arthritis [Medical Subject Headings]Female:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Autoantibodies::Antibodies Antinuclear [Medical Subject Headings]Adultmedicine.medical_specialty:Check Tags::Male [Medical Subject Headings]AntibodiesNOEstudios retrospectivosInternal medicinemedicineHumansRisk factorAdult; Aged; Antibodies Antinuclear; Arthritis; Female; Humans; Male; Middle Aged; Myositis; Retrospective Studies; Medicine (all):Persons::Persons::Age Groups::Adult [Medical Subject Headings]AgedRetrospective StudiesArtritisMyositisbusiness.industryArthritisRetrospective cohort study:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Anti Jo-1 Antisynthetase Syndromemedicine.diseaseDermatologyRheumatology:Check Tags::Female [Medical Subject Headings]Miositisantisynthetase syndromebusiness
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