MOLECULAR SIGNALLING RESPONSE TO SHORT DURATION HIGH INTENSITY/LOW VOLUME RESISTANCE TRAINING IN HUMAN SKELETAL MUSCLE.

Introduction Resistance training (RT) is one of the most important stimuli for muscle hypertrophy, but it may play also an important role on weight loss and fat acid (FA) oxidation increase. It has been largely demonstrated that RT affects anabolic signalling molecule phosphorylation but, considering the numerous variables of RT, the differences between training modalities has been till now poorly investigated. The aim of this study was to assess Akt, 4EBP1, S6 and AMPK, ACC signalling after a single bout of high-intensity resistance training (HIRT) and of traditional resistance training (TRT). Methods 12 healthy subjects performed in two different moments and with different legs HIRT and T…