Nutritional prevention by dietary resveratrol as chemopreventive agent: application to colorectal cancers

2006

Resveratrol (3,4',5 tri-hydroxystilbene) is a plant phytoalexin produced in massive amount in grapevine skin in response to stress such as UV, phytosanitary treatment, and mostly following infection by Bothrytis cinerea. In this later case, the production of resveratrol inhibits the proliferation of the pathogen, thereby acting as a natural antifungal. Many experimental studies have reported interesting properties of trans-resveratrol as a preventive agent against important pathologies i.e. vascular diseases, cancers, viral infection or neurodegenerative processes. In addition, several epidemiological studies indicated that resveratrol would be the main microcomponent of wine leading health…