Osmotic conditions in rheologic properties of erytrocites

Abstract The decreasing viability and in vivo survival of red blood cells, RBCs, observed in blood bank-storage are due to alterations in their rheologic properties and metabolic status. However, there is a lack of electrokinetic experiments with erythrocytes by the screening produced by the high concentration of buffer required to keep the isoosmotic conditions. Electrokinetic measurements in a wide range of sodium chloride and tetrasodium pyrophosphate are undertaken on liposomes as cell models, and in order to get an aqueous media suitable for maintaining osmotic conditions and allowing electrophoretic mobility measurements as well, advantage has been taken of dextrose properties. Measur…