0000000000214443
AUTHOR
V. Sparacino
Lipid and Apoprotein Profile in Renal Transplant Recipients
Lipid and apoprotein profiles of renal transplant recipients were compared with that of a group of uremic patients on hemodialytic treatment. Total cholesterol, HDL-cholesterol, apo AI and apo B were higher and triglycerides, apo CII, apo CIII and apo E lower in renal transplant patients. Type IIa and IIb were the prevalent phenotypes in renal transplant recipients.
A randomized trial of steroid avoidance in renal transplant patients treated with everolimus and cyclosporine
In this randomized trial renal transplant recipients were treated with basiliximab, everolimus 3 mg/day, low-dose CsA. At transplantation, patients were randomized to stop steroids at the seventh day (group A) or to continue oral steroids in low doses (group B). Of the 113 patients enrolled, 65 were randomized to group A and 68 to group B. All patients were followed for 2 years. During the study 28 (43%) group A patients required reintroduced corticosteroids. One patient died, in group B. The Graft survival rate was 97% in group A and 90% in group B. There were more biopsy-proven rejections in group A (32% vs 16%; P = .044). The mean creatinine clearance was 54 +/- 21 mL/min in group A vs 5…