0000000000217112

AUTHOR

Annarita Mazzariol

0000-0003-2729-1007

showing 2 related works from this author

Etestw versus broth microdilution for ceftaroline MIC determination with Staphylococcus aureus: Results from PREMIUM, a European multicentre study

2017

Objectives: To compare the concordance of ceftaroline MIC values by reference broth microdilution (BMD) and Etest (bioMérieux, France) for MSSA and MRSA isolates obtained from PREMIUM (D372SL00001), a European multicentre study. Methods: Ceftaroline MICs were determined by reference BMD and by Etest for 1242 MSSA and MRSA isolates collected between February and May 2012 from adult patients with community-acquired pneumonia or complicated skin and soft tissue infections; tests were performed across six European laboratories. Selected isolates with ceftaroline resistance in broth (MIC >1 mg/L) were retested in three central laboratories to confirm their behaviour. Results: Overall concordance…

Male0301 basic medicineCephalosporinPharmacologiemedicine.disease_causeCommunity-acquired pneumoniaPneumonia StaphylococcalCommunity-Acquired InfectionPharmacology (medical)Pathologie maladies infectieusesAged 80 and overMicrobial Sensitivity TestBroth microdilutionCeftalorine; Staphylococcus aureus; PREMIUM STUDY GROUPCeftalorineMiddle AgedAnti-Bacterial AgentsCommunity-Acquired InfectionsEuropeInfectious DiseasesStaphylococcus aureusStaphylococcus aureuStaphylococcal Skin InfectionsFemaleHumanAdultMicrobiology (medical)medicine.medical_specialtyStaphylococcus aureusAdolescentmedicine.drug_classCephalosporin030106 microbiologyPREMIUM STUDY GROUPMicrobial Sensitivity TestsStaphylococcal Skin InfectionMicrobiologyYoung Adult03 medical and health sciencesInternal medicineAnti-Bacterial AgentmedicineHumansEtestAgedPharmacologyAdult patientsbusiness.industrybiochemical phenomena metabolism and nutritionmedicine.diseasebacterial infections and mycosesMethicillin-resistant Staphylococcus aureusCephalosporinsMethicillin Susceptible Staphylococcus Aureusbusiness
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A novel VIM‐type metallo‐beta‐lactamase (VIM‐14) in a Pseudomonas aeruginosa clinical isolate from a neonatal intensive care unit

2011

AbstractA Pseudomonas aeruginosa highly resistant to carbapenems was isolated in a neonatal intensive care unit in Palermo, Italy. The strain was found to carry a novel VIM‐type enzyme, classified as VIM‐14. The novel enzyme differs from VIM‐4 in a G31S mutation. VIM‐14 was harboured in a class 1 integron with a new organization. The integron carried the genes aac7, blaVIM‐14, blaOXA‐20 and aac4 in that order.

DNA BacterialMicrobiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaNeonatal intensive care unitSettore MED/17 - Malattie Infettivemetallo-b-lactamaseAntibiotic resistancemetallo-β-lactamasemedicine.medical_treatmentMolecular Sequence DataMicrobial Sensitivity TestsBiologySettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeIntegronbeta-LactamasesIntegronscarbapenemlaw.inventionMicrobiologyAntibiotic resistancelawDrug Resistance Multiple BacterialIntensive Care Units Neonatalpolycyclic compoundsmedicineHumansVIM-14Antibacterial agentBase SequencePseudomonas aeruginosaInfant Newbornmetallo‐β‐lactamaseAntibiotic resistance; carbapenems; metallo-b-lactamase; Pseudomonas aeruginosa; VIM-14Sequence Analysis DNAGeneral Medicinebiochemical phenomena metabolism and nutritionbacterial infections and mycosesbiology.organism_classificationIntensive care unitInfectious DiseasesPseudomonas aeruginosaBeta-lactamasebiology.proteinbacteriacarbapenemsVIM‐14PseudomonadaceaeClinical Microbiology and Infection
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