Modelling analysis of centroid curves of olfactory habituation in humans

Indexation en cours.; International audience; Previously published experiments established the time-course of olfactory habituation in humans, and extracted 3 centroid curves from clustering analysis that reflected high, middle and low habituation. The aim of the current theoretical study was to further analyse these previous experimental data by developing a mathematical modelling analysis designed for fitting the 3 curves from a general equation. After adjusting equation parameters for each curve, fitting equation outcomes on experimental data yielded high correlation coefficients of 0.9997 – 0.9995 – 0.9962, respectively. A model-based interpretation of olfactory-habituation centroid cur…