0000000000217707

AUTHOR

Filippo Ansaldi

showing 11 related works from this author

Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project

2019

Contains fulltext : 206779.pdf (Publisher’s version ) (Open Access) BACKGROUND: The objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe. METHODS: A multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries, representing the first phase of the candidemia/intra-abdominal candidiasis in European ICU project (EUCANDICU). RESULTS: During the study period, 570 episodes of ICU-acquired IC were observed, with a cumulative incidence of 7.07 episodes per 1000 ICU admissions, with important between-center variability. Separated, non-mutually exclusive cumulative incidences of candide…

MaleOutcome Assessmentlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]MULTICENTERCritical Care and Intensive Care Medicinelaw.invention610 Medical sciences Medicine0302 clinical medicineRetrospective StudieRisk FactorslawOutcome Assessment Health CareEPIDEMIOLOGYMedicineCumulative incidencePREDICTORSCandidaMedicine(all)Cross InfectionIncidenceIncidence (epidemiology)lcsh:Medical emergencies. Critical care. Intensive care. First aidCandidiasisMiddle AgedIntensive care unitEuropeIntensive Care UnitsAbdominal candidiasis; Candida; Candidemia; Candidiasis; ICU; Incidence; Aged; Candidiasis Invasive; Cross Infection; Europe; Female; Humans; Incidence; Intensive Care Units; Male; Middle Aged; Outcome Assessment Health Care; Retrospective Studies; Risk FactorsCandidiasiFemaleSOFA scoreLife Sciences & BiomedicineHumanAbdominal candidiasismedicine.medical_specialtyInvasiveIntensive Care Unit610Abdominal candidiasis Candida Candidemia Candidiasis ICU Incidence03 medical and health sciencesCritical Care MedicineGeneral & Internal MedicineIntensive careSettore MED/41 - ANESTESIOLOGIAMANAGEMENTHumansCandidiasis InvasiveAgedRetrospective StudiesScience & TechnologyAbdominal candidiasis; Candida; Candidemia; Candidiasis; ICU; Incidencebusiness.industrySeptic shockINTRAABDOMINAL CANDIDIASISResearchCandidemia030208 emergency & critical care medicineRetrospective cohort studylcsh:RC86-88.9Odds ratiomedicine.diseaseHealth Carelnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]ICUEmergency medicineAbdominal candidiasibusinessCritical Care
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Influenza control in the 21st century: Optimizing protection of older adults

2009

Older adults (> or =65 years of age) are particularly vulnerable to influenza illness. This is due to a waning immune system that reduces their ability to respond to infection, which leads to more severe cases of disease. The majority ( approximately 90%) of influenza-related deaths occur in older adults and, in addition, catastrophic disability resulting from influenza-related hospitalization represents a significant burden in this vulnerable population. Current influenza vaccines provide benefits for older adults against influenza; however, vaccine effectiveness is lower than in younger adults. In addition, antigenic drift is also a concern, as it can impact on vaccine effectiveness due t…

DiseaseVaccines AttenuatedAntigenic driftDNA vaccinationAdjuvants ImmunologicCost of IllnessImmunityInfluenza HumanHumansMedicineAntigens ViralAgedAttenuated vaccineGeneral VeterinaryGeneral Immunology and Microbiologybusiness.industryHealth PolicyImmunogenicityVaccinationPublic Health Environmental and Occupational HealthVaccines VirosomeVaccinationInfectious DiseasesImmunizationInfluenza VaccinesImmunologyMolecular MedicinebusinessVaccine
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Attitudes and beliefs on influenza vaccination during the covid-19 pandemic: Results from a representative italian survey

2020

The last 2019/20 northern hemisphere influenza season overlapped with the first wave of coronavirus disease 2019 (COVID-19) pandemic. Italy was the first western country where severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread to a significant extent. In this representative cross-sectional survey, we aimed to describe some opinions and attitudes of the Italian general population towards both influenza vaccination and the COVID-19 pandemic, and to identify potential modifiers of the decision-making process regarding the uptake of the 2020/21 influenza vaccine. A total of 2543 responses were analyzed. Although most (74.8%) participants valued influenza vaccination positively …

0301 basic medicineCoronavirus disease 2019 (COVID-19)Influenza vaccineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ImmunologyPopulationlcsh:MedicineInfluenza seasonArticleOddsSurvey.03 medical and health sciences0302 clinical medicinevaccineDrug DiscoveryPandemicMedicinePharmacology (medical)030212 general & internal medicineeducationSurveySettore MED/42 - IGIENE GENERALE E APPLICATAPharmacologyeducation.field_of_studyattitudesbusiness.industrylcsh:Rvirus diseasesCOVID-19InfluenzaVaccination030104 developmental biologyInfectious Diseasesinfluenza; COVID-19; vaccine; survey; vaccine hesitancy; attitudes; ItalyAttitudeItalyvaccine hesitancybusinessDemography
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Italian Health Care Workers’ Knowledge, Attitudes, and Practices Regarding Human Papillomavirus Infection and Prevention

2020

Objective: To assess healthcare workers&rsquo

AdultMaleHealth Knowledge Attitudes Practicemedicine.medical_specialtyHPVknowledgegenetic structuresHealth PersonnelHealth Toxicology and MutagenesisUterine Cervical Neoplasmslcsh:MedicineScientific literatureimmunizationSettore MED/42 - Igiene Generale E ApplicataArticle03 medical and health sciences0302 clinical medicinepreventionAttitude Awareness Healthcare workers HPV Immunization Knowledge Practice Prevention Sexually transmitted infection Adult Cross-Sectional Studies Female Italy Middle Aged Papillomavirus Vaccines Papillomavirus Infections Uterine Cervical NeoplasmsSurveys and QuestionnairesvaccineIntervention (counseling)Health caremedicineHumansAttitude; Awareness; Healthcare workers; HPV; Immunization; Knowledge; Practice; Prevention; Sexually transmitted infection; VaccineawarenessPapillomavirus Vaccinessexually transmitted infection030212 general & internal medicineHuman papillomavirusbusiness.industryhealthcare workersPapillomavirus Infectionslcsh:RPublic Health Environmental and Occupational HealthMiddle AgedProduct characteristicspracticeCross-Sectional StudiesItaly030220 oncology & carcinogenesisFamily medicineattitudeMulticenter surveyPropensity score matchingFemalebusinessInternational Journal of Environmental Research and Public Health
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Assessment of Knowledge, Attitudes, and Propensity towards HPV Vaccine of Young Adult Students in Italy

2020

Background: Human Papillomavirus (HPV) is a common sexually transmitted infection (STI), representing the main cause of genital warts and cervical cancer. This cross-sectional study evaluated knowledge and attitudes about HPV infection, related diseases, and prevention and propensity towards HPV vaccine among undergraduate students. Methods: An online and written survey about HPV and its prevention, targeted to young adults of both genders, was addressed to students attending health sciences and other schools at Universities of Genoa and Bari. Results: The overall median knowledge and attitude scores were 56.3% (25&ndash

young adultsmedicine.medical_specialtyHPVknowledgeMultivariate analysisstudentImmunologylcsh:MedicineArticleGenital warts03 medical and health sciences0302 clinical medicinepreventionDrug DiscoveryHealth caremedicinePharmacology (medical)030212 general & internal medicinesexually transmitted infectionYoung adultSocioeconomic statusPharmacologyCervical cancerbusiness.industrylcsh:RHPV infectionvirus diseasesmedicine.diseasevaccinationfemale genital diseases and pregnancy complicationspracticeVaccinationInfectious Diseases030220 oncology & carcinogenesisFamily medicineattitudebusinessAttitude; HPV; Knowledge; Practice; Prevention; Sexually transmitted infection; Student; Vaccination; Young adultsVaccines
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Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisatio…

2017

Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection. A 6-year retrospective surveillance study was conducted between 2010 and 2016 in 2 large administrative regions of Italy, located in the north (Liguria) and in the south (Sicily) of the country, to describe the burden and epidemiology of both B/Victoria and B/Yamagata lineages in different healthcare settings. Influenza B viruses were detected in 5 of 6 seasonal outbreaks, exceeding influenza A during the season 2012–2013. Most of influenza B infections were found…

Male0301 basic medicinevirusesInfluenza B viruDisease OutbreaksHuman health0302 clinical medicineRetrospective StudieEpidemiologyImmunology and Allergy030212 general & internal medicinehospitalChildSicilyB/Victoriaeducation.field_of_studyDisease OutbreakVaccinationvirus diseasesB/Victoria; B/Yamagata; community; hospital; Influenza type B; lineage; vaccine-mismatch; Immunology and Allergy; Immunology; Pharmacologyvaccine-mismatchInfluenza type BInfluenza A viruInfluenza A virusInfluenza VaccinesChild PreschoolcommunityCommunity settingFemaleSeasonsInfluenza VaccineHumanResearch Papermedicine.medical_specialty030106 microbiologyImmunologyPopulationEpidemic03 medical and health sciencesInfluenza HumanmedicineHumansEpidemicseducationRetrospective StudiesPharmacologyInfluenza immunisationbusiness.industryOutbreakInfluenza aVirologyInfluenza B virusVaccine mismatchSeasonbusinessB/YamagatalineageDemographyHuman Vaccines & Immunotherapeutics
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Immunization Campaigns and Strategies against Human Papillomavirus in Italy: The Results of a Survey to Regional and Local Health Units Representativ…

2019

Objective. The study aimed to assess the impact of HPV immunization campaigns organizational aspects, the characteristics of immunization program (vaccination targets and type of offer), and communicative strategies adopted by four Italian administrative regions on vaccination coverage observed. Methods. From November 2017 to March 2018, regional and Local Health Units (LHUs) representatives were invited to complete an online survey including 54 questions evaluating vaccination invite systems, access systems to vaccination centres, reminder and recall systems, and adverse events surveillance. An overall descriptive analysis was conducted. Since observed vaccine coverage (VC) obtained in fem…

AdultMalemedicine.medical_specialtyArticle SubjectImmunization registryMEDLINElcsh:MedicineGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicine030225 pediatricsHealth careHumansMedicinePapillomavirus Vaccines030212 general & internal medicineHuman papillomavirusSurveyPapillomaviridaeCopaymentGeneral Immunology and MicrobiologyDescriptive statisticsImmunization Campaigns and StrategieImmunization Programsbusiness.industryPapillomavirus InfectionsVaccinationlcsh:RAdult; Female; Humans; Immunization Programs; Italy; Male; Papillomaviridae; Papillomavirus Infections; Papillomavirus Vaccines; VaccinationGeneral MedicineVaccinationHuman PapillomaviruItalyImmunizationFamily medicineFemalebusinessResearch ArticleBioMed Research International
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The molecular epidemiology and evolutionary dynamics of influenza B virus in two Italian regions during 2010-2015: The experience of Sicily and Ligur…

2016

Molecular epidemiology of influenza B virus remained poorly studied in Italy, despite representing a major contributor to seasonal epidemics. This study aimed to reconstruct the phylogenetic relationships and genetic diversity of the hemagglutinin gene sequences of 197 influenza B strains circulating in both Southern (Sicily) and Northern (Liguria) Italy between 2010 and 2015. Upper respiratory tract specimens of patients displaying symptoms of influenza-like illness were screened by real-time RT-PCR assay for the presence of influenza B virus. PCR-positive influenza B samples were further analyzed by sequencing. Neighbor-joining phylogenetic trees were constructed and the amino-acid alignm…

0301 basic medicineInfluenza ViruslineagesHemagglutinin Glycoproteins Influenza VirusLiguriaSettore MED/42 - Igiene Generale E Applicatamolecular epidemiologyCatalysilcsh:Chemistryviral evolutionCladeinfluenza BSicilylcsh:QH301-705.5PhylogenySpectroscopyPhylogenetic treeinfluenza B; lineages; viral evolution; surveillance; molecular epidemiology; influenza-like illness; Sicily; Liguria; ItalyComputer Science Applications1707 Computer Vision and Pattern RecognitionGeneral MedicineBiological EvolutionComputer Science ApplicationsInfluenza B; Influenza-like illness; Italy; Liguria; Lineages; Molecular epidemiology; Sicily; Surveillance; Viral evolution; Biological Evolution; Genetic Variation; Hemagglutinin Glycoproteins Influenza Virus; Humans; Influenza B virus; Influenza Human; Italy; Molecular Epidemiology; Sicily; Phylogeny; Catalysis; Molecular Biology; Computer Science Applications1707 Computer Vision and Pattern Recognition; Spectroscopy; Physical and Theoretical Chemistry; Organic Chemistry; Inorganic ChemistryInfluenza B; Influenza-like illness; Italy; Liguria; Lineages; Molecular epidemiology; Sicily; Surveillance; Viral evolution; Catalysis; Molecular Biology; Spectroscopy; Computer Science Applications1707 Computer Vision and Pattern Recognition; Physical and Theoretical Chemistry; Organic Chemistry; Inorganic ChemistryItalyViral evolutionsurveillanceHumanHemagglutinin Glycoproteinsinfluenza-like illnessHemagglutinin (influenza)BiologyArticleCatalysisVirusInorganic Chemistry03 medical and health sciencesLineagePhylogeneticsInfluenza HumanHumansPhysical and Theoretical ChemistryMolecular BiologyInfluenza-like illneInfluenza-like illnessMolecular epidemiologyOrganic ChemistryGenetic VariationVirologyInfluenzaInfluenza B virus030104 developmental biologylcsh:Biology (General)lcsh:QD1-999biology.protein
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Burden and Prevention of HPV. Knowledge, Practices and Attitude Assessment Among Pre-Adolescents and their Parents in Italy

2020

Despite infections due to HPV nowadays represent the most common sexually transmitted diseases worldwide with recognized effective and safe preventive strategies, knowledge, attitudes; however, awareness on HPV is considerably low. The present study has two main objectives: 1. To conduct a literature review to analyze the evolution of preventive tools, the complexity of the vaccine choice process, and the challenges posed by HPV vaccine hesitancy and refusal among pre-adolescents and their parents; 2. To assess knowledge, practices and attitudes toward HPV infection and vaccination in a sample of Italian pre-adolescents and their parents. The observational study was carried out through the…

AdultMaleParentsHealth Knowledge Attitudes Practicemedicine.medical_specialtyHPVknowledgePre adolescentsTarget populationAdolescentsArticle03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesIntervention (counseling)Drug DiscoverymedicineHumansPapillomavirus VaccinesAdolescents; Attitude; HPV; Knowledge; Parents; Practice; Vaccine030212 general & internal medicineChildAgedPharmacologybusiness.industryPapillomavirus InfectionsVaccinationHPV infectionMiddle AgedPatient Acceptance of Health Caremedicine.diseasepracticevaccine.VaccinationparentCross-Sectional StudiesItaly030220 oncology & carcinogenesisFamily medicineadolescentattitudeFemaleHealth educationObservational studybusinessVaccineHpv knowledge
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Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study

2022

INTRODUCTION: Intra-abdominal infections represent the second most frequently acquired infection in the intensive care unit (ICU), with mortality rates ranging from 20% to 50%. Candida spp. may be responsible for up to 10-30% of cases. This study assesses risk factors for development of intra-abdominal candidiasis (IAC) among patients admitted to ICU. METHODS: We performed a case-control study in 26 European ICUs during the period January 2015-December 2016. Patients at least 18 years old who developed an episode of microbiologically documented IAC during their stay in the ICU (at least 48 h after admission) served as the case cohort. The control group consisted of adult patients who did no…

Microbiology (medical)MORTALITYInvasive candidiasiCandida; Intra-abdominal infection; Invasive candidiasis; Risk factorsCONTROLLED-TRIALCASPOFUNGINCANDIDEMIAInvasive candidiasisInfectious Diseaseslnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]Intra-abdominal infectionRisk factorsINFECTIONSMANAGEMENTEPIDEMIOLOGYPREDICTORSCONSENSUSCRITICALLY III PATIENTSCandida
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Hospital discharges-based search of acute flaccid paralysis cases 2007-2016 in Italy and comparison with the National Surveillance System for monitor…

2019

Abstract Background Acute flaccid paralysis (AFP) surveillance has been adopted globally as a key strategy for monitoring the progress of the polio eradication initiative. Hereby, to evaluate the completeness of the ascertainment of AFP cases in Italy, a hospital-discharges based search was carried out. Methods AFP cases occurring between 2007 and 2016 among children under 15 years of age were searched in the Italian Hospital Discharge Records (HDR) database using specific ICD-9-CM diagnostic codes. AFP cases identified between 2015 and 2016 were then compared with those notified to the National Surveillance System (NSS). Results Over a 10-year period, 4163 hospital discharges with diagnosi…

MaleSettore MED/07 - Microbiologia E Microbiologia ClinicaPediatricsERADICATIONAcute flaccid paralysi0302 clinical medicineWORLDWIDEEpidemiologyParalysisMedicine030212 general & internal medicineChildPublic Environmental & Occupational Health0303 health sciencesPoliolcsh:Public aspects of medicineHospital RecordsAcute flaccid paralysisPatient DischargePoliomyelitisItalyChild PreschoolPopulation SurveillanceFemaleDiagnosis codemedicine.symptomHospital discharge recordLife Sciences & BiomedicineEncephalitisResearch ArticleHumanAcute flaccid paralysismedicine.medical_specialtyAdolescentMyelitis03 medical and health sciencesPoliomyelitis eradicationHospital discharge recordsHospital RecordHumansParalysisNational surveillance systemPreschoolScience & Technology030306 microbiologybusiness.industryPublic Health Environmental and Occupational HealthInfantlcsh:RA1-1270Acute flaccid paralysis; Hospital discharge records; National surveillance system; Polio; Adolescent; Child; Child Preschool; Female; Hospital Records; Humans; Infant; Italy; Male; Paralysis; Patient Discharge; Poliomyelitis; Population Surveillancemedicine.diseaseParalysiPoliomyelitibusinessPoliomyelitis
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