0000000000218191
AUTHOR
M. Musumeci
Carotid plaque detection improves the predictve value of CHA2DS2-VASc score in patients with non-valvular atrial fibrilation: The ARAPACIS Study
Abstract Background and aims Vascular disease (VD), as assessed by history of myocardial infarction or peripheral artery disease or aortic plaque, increases stroke risk in atrial fibrillation (AF), and is a component of risk assessment using the CHA 2 DS 2 -VASc score. We investigated if systemic atherosclerosis as detected by ultrasound carotid plaque (CP) could improve the predictive value of the CHA 2 DS 2 -VASc score. Methods We analysed data from the ARAPACIS study, an observational study including 2027 Italian patients with non-valvular AF, in whom CP was detected using Doppler Ultrasonography. Results VD was reported in 351 (17.3%) patients while CP was detected in 16.6% patients. Ad…
Deep sea tests of a prototype of the KM3NeT digital optical module
SIRE(opens in a new window)|View at Publisher| Export | Download | Add to List | More... European Physical Journal C Volume 74, Issue 9, 1 September 2014, 8p Deep sea tests of a prototype of the KM3NeT digital optical module: KM3NeT Collaboration (Article) Adrián-Martínez, S.a, Ageron, M.b, Aharonian, F.c, Aiello, S.d, Albert, A.e, Ameli, F.f, Anassontzis, E.G.g, Anghinolfi, M.h, Anton, G.i, Anvar, S.j, Ardid, M.a, de Asmundis, R.k, Balasi, K.l, Band, H.m, Barbarino, G.kn, Barbarito, E.o, Barbato, F.kn, Baret, B.p, Baron, S.p, Belias, A.lq, Berbee, E.m, van den Berg, A.M.r, Berkien, A.m, Bertin, V.b, Beurthey, S.b, van Beveren, V.m, Beverini, N.st, Biagi, S.uv, Bianucci, S.t, Billault, M.b,…
First results of the Instrumentation Line for the deep-sea ANTARES neutrino telescope
In 2005, the ANTARES Collaboration deployed and operated at a depth of 2500 m a so-called Mini Instrumentation Line equipped with Optical Modules (MILOM) at the ANTARES site. The various data acquired during the continuous operation from April to December 2005 of the MILOM confirm the satisfactory performance of the Optical Modules, their front-end electronics and readout system, as well as the calibration devices of the detector. The in-situ measurement of the Optical Module time response yields a resolution better than 0.5 ns. The performance of the acoustic positioning system, which enables the spatial reconstruction of the ANTARES detector with a precision of about 10 cm, is verified. T…
Major adverse cardiovascular events in non-valvular atrial fibrillation with chronic obstructive pulmonary disease: the ARAPACIS study
Chronic obstructive pulmonary disease (COPD) increases the risk of mortality in non-valvular atrial fibrillation (NVAF) patients. Data on the relationship of COPD to major cardiovascular events (MACE) in AF have not been defined. The aim of the study is to assess the predictive value of COPD on incident MACE in NVAF patients over a 3-year follow-up. In the Atrial Fibrillation Registry for Ankle-Brachial Index Prevalence Assessment-Collaborative Italian Study (ARAPACIS) cohort, we evaluate the impact of COPD on the following clinical endpoints: MACE (including vascular death, fatal/non-fatal MI and stroke/TIA), cardiovascular (CV) death and all-cause mortality. Among 2027 NVAF patients, pati…
Deep sea tests of a prototype of the KM3NeT digital optical module: KM3NeT Collaboration
The first prototype of a photo-detection unit of the future KM3NeT neutrino telescope has been deployed in the deep waters of the Mediterranean Sea. This digital optical module has a novel design with a very large photocathode area segmented by the use of 31 three inch photomultiplier tubes. It has been integrated in the ANTARES detector for in-situ testing and validation. This paper reports on the first months of data taking and rate measurements. The analysis results highlight the capabilities of the new module design in terms of background suppression and signal recognition. The directionality of the optical module enables the recognition of multiple Cherenkov photons from the same $^{40…
ANTARES: The first undersea neutrino telescope
The ANTARES Neutrino Telescope was completed in May 2008 and is the first operational Neutrino Telescope in the Mediterranean Sea. The main purpose of the detector is to perform neutrino astronomy and the apparatus also offers facilities for marine and Earth sciences. This paper describes the design, the construction and the installation of the telescope in the deep sea, offshore from Toulon in France. An illustration of the detector performance is given. © 2011 Elsevier B.V. All rights reserved.