0000000000218427
AUTHOR
Laura Diaz
WITHDRAWN: Systems Biology and Immune Aging
The Publisher regrets that this article is an accidental duplication of anarticle that has already been published, http://dx.doi.org/10.1016/j.imlet.2014.09.009 . The duplicate article has therefore been withdrawn.
Systems Biology and immune aging
Many alterations of innate and adaptive immunity are common in the aging population, which reflect a deterioration of the immune system, and have lead to the terms "immune aging" or "immunosenescence". Systems Biology aims to the comprehensive knowledge of the structure, dynamics, control and design that define a given biological system. Systems Biology benefits from the continuous advances in the omics sciences, based on high-throughput and high-content technologies, as well as on bioinformatic tools for data mining and integration. The Systems Biology approach is becoming gradually used to propose and to test comprehensive models of aging, both at the level of the immune system and the wh…
La identidad a través de la pose, del retrato burgués decimonónico al selfie
[EN] This work articulates some typologies that from the point of view of expression and pose encode the identity of subjects portrayed in the 19th century. We also study how these 19th century typologies survive in the 20th century by virtue of relationships of inheritance and filiation. We will focus on the bourgeois normative portrait, on the artistic portrait and the police portrait, one of the manifestations of otherness. To conclude, we will reflect on the ambivalent nature of selfies, an emergent and genuinely digital typology related most directly with self-portraits, but using codes of expression, function and diffusion which are different from previous ones.
Clinical and Biological Characterization of Patients with Low/Intermediate-1 Risk Myelodysplastic Syndrome and Iron Overload
Abstract Abstract 4956 Introduction. Patients with Myelodysplastic Syndrome (MDS) are susceptible to developing iron overload as a response to the red blood cell (RBC) transfusions and ineffective hematopoiesis. This iron overload (IOL) is characterized by an increase in oxygen-reactive species accompanied by a decrease in antioxidants, and results in hepatic, cardiac and endocrine disorders, as well as an increased risk of infection. Ineffective hematopoiesis promotes iron absorption at intestinal level. This process is enhanced by the presence of mutations in the hereditary hemochromatosis gene (HFE). This study aims to define the features that accompany patients with iron overload, compa…
Real-time cytometric assay of nitric oxide and superoxide interaction in peripheral blood monocytes: A no-wash, no-lyse kinetic method
Background Nitric oxide (NO) and its related reactive nitrogen species (RNS) and reactive oxygen species (ROS) are crucial in monocyte responses against pathogens and also in inflammatory conditions. Central to both processes is the generation of the strong oxidant peroxynitrite (ONOO) by a fast reaction between NO and superoxide anion. ONOO is a biochemical junction for ROS- and RNS cytotoxicity and causes protein nitrosylation. Circulating by-products of protein nitrosylation are early biomarkers of inflammation-based conditions, including minimal hepatic encephalopathy in cirrhotic patients (Montoliu et al., Am J Gastroenterol 2011; 106:1629–1637). In this context, we have designed a nov…
Special Olympics un medio para la justicia social en la India rural
El siguiente Poster muestra el trabajo realizado por la Fundación Vicente Ferrer en su proyecto de deporte y discapacidad, en el Estado de Andhra Pradesh (India), donde las personas con diversidad funcional están totalmente estigmatizadas socialmente. Este programa desarrollado desde 2010 de Special Olympics (SO) ha contribuido a promover la igualdad de condiciones, derechos y oportunidades de las personas con discapacidad intelectual. El objetivo de esta investigación es analizar y confirmar que el deporte es una herramienta de integración social en la india rural. El estudio del caso de Kullaymma, es representativo del conjunto de niños y niñas con discapacidad intelectual integrantes del…
From social stigma to family referent, boccia for a change on the way of thinking
The aim of this study was to assess the impact of the practice of Boccia (adapted sport) with children aged between 4 and 14 years old with cerebral palsy in rural India and the changes that this implies in social recognition and quality of family life. This study took place between January 2015 and February 2016. The research aims to fill the knowledge gap given the little information that exists on the importance of the context, specifically in the case of a family with a disabled person. This project is part of the "Family Centred Program" and is based on the use of a structured interview called Family Quality of Life McWilliams (FaQuOL). A statistical analysis using SPSS was conducted t…