0000000000220726
AUTHOR
F. Pardo
Pain in paediatric hospital units
BRONCHIAL ARTERY EMBOLIZATION IN CYSTIC FIBROSIS PATIENTS: A SINGLE CENTRE EXPERIENCE
Anomalous origin of bronchial arteries in patients with cystic fibrosis: therapeutic implications for embolisation.
Bronchial artery embolisation (BAE) is an accepted method of controlling haemoptysis in patients with cystic fibrosis. However, anomalous origin of the bronchial arteries, documented in anatomical and angiographic studies, makes the procedure more difficult and increases the number of recurrences. Clinical records and films from three patients affected by cystic fibrosis with haemoptysis, in which the origin of the bleeding vessels was considered anomalous, out of a total of seven patients who underwent BAE, were reviewed. In two patients the source of bleeding was identified from, respectively, the left and the right internal mammary artery and in one from the left thyrocervical trunk. All…
LA “MALATTIA DEL BACIO SALATO”: STUDIO SULLA QUALITÀ DI VITA IN PAZIENTI ADULTI AFFETTI DA FIBROSI CISTICA
I recenti progressi nella diagnosi e nel trattamento della Fibrosi Cistica (FC) hanno permesso un miglioramento della vita media e un importante aumento della percentuale di individui con FC che raggiungono e vivono l’età adulta; obiettivo dello studio è valutare il vissuto emotivo e psicologico dei pazienti adulti con FC che afferiscono regolarmente al Centro di Palermo, Ipotesi: il presente contributo rappresenta il primo studio esplorativo sulla relazione tra qualità di vita, alessitimia e resilienza in pazienti adulti affetti da FC. La nostra ipotesi è che buone capacità resilienti e adeguate capacità di regolare le emozioni possano fungere da fattori protettivi di salute, contribuendo …
TH-302 + Gemcitabine (G + T) vs Gemcitabine (G) in Patients with Previously Untreated advanced Pancreatic Cancer (PAC)
ABSTRACT Background TH-302 is a hypoxia targeted prodrug with a hypoxia-triggered 2-nitroimidazole component designed to release the DNA alkylator, bromo-isophosphoramide mustard (Br-IPM), when reduced in severe hypoxia. A randomized Phase 2B study (NCT01144455) was conducted to assess the benefit of G + T to standard dose G as first-line therapy of PAC. Materials and methods An open-label multi-center study of two dose levels of TH-302 (240 mg/m2 or 340 mg/m2) in combination with G versus G alone (randomized 1:1:1). G (1000 mg/m2) and T were administered IV over 30-60 minutes on Days 1, 8 and 15 of a 28-day cycle. Patients on the G could crossover after progression and be randomized to a G…
La "malattia del bacio salato": studio sulla qualità di vita in pazienti adulti affetti da Fibrosi Cistica
Bronchial to subclavian shunt in a CF patient. A potential pitfall for embolization
Bronchial artery embolization is a well accepted and widely used technique in the management of massive haemoptysis in cystic fibrosis (CF). It can be a complex procedure requiring a deep knowledge of the bronchial artery anatomy including the possible bronchial anastomoses. We report a case of complex vascular anatomy of the left bronchial artery with multiple anastomoses with the ipsilateral subclavian artery as cause of non-attempted embolization. © 2003 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.
Serum interleukin-6 levels are elevated in women with minimal-mild endometriosis.
BACKGROUND: There is a need for a reliable marker of endometriosis, especially in early stages of peritoneal disease during which imaging is not effective. The use of serum interleukin (IL)-6 as a marker is controversial. To readdress the matter, patients undergoing laparoscopy were prospectively evaluated for serum IL-6 levels. MATERIALS AND METHODS: A total of 119 women 31 years old who underwent laparoscopy were divided into groups: control patients (n = 38) with no pathologic findings; endometriosis sufferers (n = 47) with minimal-mild (MM, n = 11) or moderate-severe (MS, n = 36) endometriosis; uterine myomas (n = 13) and benign ovarian pathologies (n = 21). Blood was drawn on cycles da…
Analisi retrospettiva delle embolizzazioni bronchiali in Fibrosi cistica e follow up a lungo termine
Lateral thoracic artery embolization in cystic fibrosis. A case report
We report the embolization of an aberrant origin of haemoptysis - from the internal branch of the lateral thoracic artery - in a patient affected by cystic fibrosis. The technical implications for embolotheraphy in case of an aberrant origin of a haemorrhage are emphasized. Many different systemic arteries may contribute to the blood supply of the lung and many connections may exist between the systemic, bronchial and pulmonary circulations. The presence of non-bronchial systemic arteries supply should be investigated when inconclusive findings are seen during bronchial artery embolization for haemoptysis.