0000000000226179

AUTHOR

Frido Himmelsbach

showing 2 related works from this author

Reduced secretion of proinflammatory cytokines of monosodium urate crystal‐stimulated monocytes in chronic renal failure: an explanation for infreque…

2000

In gouty arthritis, monosodium urate (MSU) crystals interact with monocytes and neutrophils to produce inflammatory reactions associated with acute synovitis. In patients with end-stage renal disease (ESRD), gouty arthritis is a rare condition despite often severe hyperuricaemia. We wondered whether differences in the secretion of proinflammatory cytokines by MSU crystal-stimulated monocytes might be one explanation for the low incidence of gouty arthritis in patients with ESRD compared with healthy controls.Thirteen patients with ESRD on intermittent haemodialysis treatment, six patients with chronic renal failure not yet on dialysis, and 15 age- and sex-matched healthy controls were exami…

AdultLipopolysaccharidesMalemusculoskeletal diseasescongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyGoutmedicine.medical_treatmentCytological TechniquesInflammationurologic and male genital diseasesProinflammatory cytokinechemistry.chemical_compoundInternal medicinemedicineHumansAgedAged 80 and overTransplantationInterleukin-6Tumor Necrosis Factor-alphabusiness.industryIncidencenutritional and metabolic diseasesMiddle Agedmedicine.diseasePathophysiologyUric AcidGoutEndocrinologyCytokinechemistryNephrologyAcute SynovitisImmunologyCytokinesKidney Failure ChronicUric acidFemaleInflammation Mediatorsmedicine.symptomCrystallizationbusinessInterleukin-1Kidney diseaseNephrology Dialysis Transplantation
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Rheopheresis in patients with ischemic diabetic foot syndrome: results of an open label prospective pilot trial.

2003

:  Rheopheresis is a specific application of membrane differential filtration, synonymous with double filtration plasmapheresis, for extracorporeal hemorheotherapy. Safety and efficacy of Rheopheresis for wound healing and skin oxygenation were investigated in patients with ischemic diabetic foot syndrome. Eight patients with type 2 diabetes mellitus and non-healing foot ulcers caused by severe ischemic diabetic foot syndrome were treated by a series of seven Rheopheresis sessions in a time span of 11 weeks. Wound healing had not been detectable under conditions of standardized wound care during at least 2 months. Wound status was classified by its morphology, severity and location, accordi…

Malemedicine.medical_specialtymedicine.medical_treatmentRheopheresisPilot ProjectsRisk AssessmentSensitivity and SpecificitySeverity of Illness IndexExtracorporealMicrocirculationWound careIschemiaDiabetes mellitusmedicineHumansProspective StudiesVascular PatencyAgedWound Healingintegumentary systembusiness.industryFootHematologyPlasmapheresisMiddle Agedmedicine.diseaseDiabetic footDiabetic FootSurgeryTreatment OutcomeAmputationNephrologyRegional Blood FlowFemaleHemofiltrationbusinessWound healingFollow-Up StudiesTherapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
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