0000000000230849

AUTHOR

Han Chen

showing 4 related works from this author

Search for Dark Matter in Events with a Hadronically DecayingWorZBoson and Missing Transverse Momentum inppCollisions ats=8  TeVwith the ATLAS Detect…

2014

A search is presented for dark matter pair production in association with a W or Z boson in pp collisions representing 20.3 fb(-1) of integrated luminosity at root s = 8 TeV using data recorded with the ATLAS detector at the Large Hadron Collider. Events with a hadronic jet with the jet mass consistent with a W or Z boson, and with large missing transverse momentum are analyzed. The data are consistent with the standard model expectations. Limits are set on the mass scale in effective field theories that describe the interaction of dark matter and standard model particles, and on the cross section of Higgs production and decay to invisible particles. In addition, cross section limits on the…

PhysicsParticle physicsLarge Hadron Collider010308 nuclear & particles physicsAtlas (topology)High Energy Physics::PhenomenologyHadronDark matterGeneral Physics and Astronomy01 natural sciencesNuclear physicsPair production0103 physical sciencesEffective field theoryHiggs bosonHigh Energy Physics::Experiment010306 general physicsBosonPhysical Review Letters
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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.

2021

AbstractLong and short sleep duration are associated with elevated blood pressure (BP), possibly through effects on molecular pathways that influence neuroendocrine and vascular systems. To gain new insights into the genetic basis of sleep-related BP variation, we performed genome-wide gene by short or long sleep duration interaction analyses on four BP traits (systolic BP, diastolic BP, mean arterial pressure, and pulse pressure) across five ancestry groups using 1 degree of freedom (1df) interaction and 2df joint tests. Primary multi-ancestry analyses in 62,969 individuals in stage 1 identified 3 novel loci that were replicated in an additional 59,296 individuals in stage 2, including rs7…

0301 basic medicineMean arterial pressureDiastoleBlood PressureBiology3121 Internal medicineGenomePolymorphism Single NucleotideElevated blood3124 Neurology and psychiatryArticleCellular and Molecular Neuroscience03 medical and health sciencesTRPC30302 clinical medicineSDG 3 - Good Health and Well-beingHumansMolecular BiologyGene030304 developmental biologyGenetics0303 health sciences[STAT.AP]Statistics [stat]/Applications [stat.AP]Short sleepSleep in non-human animalsPulse pressurePsychiatry and Mental health030104 developmental biologyBlood pressure[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsGenetic LociHypertension[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie3111 Biomedicine[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]Sleep[STAT.ME]Statistics [stat]/Methodology [stat.ME]030217 neurology & neurosurgeryGenome-Wide Association StudyMolecular psychiatry
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Measurement of Top Quark Polarization in Top-Antitop Events from Proton-Proton Collisions ats=7  TeVUsing the ATLAS Detector

2013

This Letter presents measurements of the polarization of the top quark in top-antitop quark pair events, using 4: 7 fb(-1) of proton-proton collision data recorded with the ATLAS detector at the La ...

PhysicsTop quarkParticle physicsMuon010308 nuclear & particles physicsAtlas (topology)High Energy Physics::PhenomenologyNuclear TheoryGeneral Physics and AstronomyElectronPolarization (waves)01 natural sciencesNuclear physicsPair production0103 physical sciencesPhysics::Atomic and Molecular ClustersCP violationHigh Energy Physics::ExperimentNuclear Experiment010306 general physicsLeptonPhysical Review Letters
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Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.

2016

Genome-wide association studies (GWAS) have found few common variants that influence fasting measures of insulin sensitivity. We hypothesized that a GWAS of an integrated assessment of fasting and dynamic measures of insulin sensitivity would detect novel common variants. We performed a GWAS of the modified Stumvoll Insulin Sensitivity Index (ISI) within the Meta-Analyses of Glucose and Insulin-Related Traits Consortium. Discovery for genetic association was performed in 16,753 individuals, and replication was attempted for the 23 most significant novel loci in 13,354 independent individuals. Association with ISI was tested in models adjusted for age, sex, and BMI and in a model analyzing t…

0301 basic medicineMaleInsulin Receptor Substrate ProteinsEndocrinology Diabetes and MetabolismLocus (genetics)Genome-wide association studyPolymorphism Single Nucleotide03 medical and health sciencesEndocrinology & MetabolismInsulin resistanceGenotypeInternal MedicinemedicineHumansGenetic Predisposition to DiseaseGenetic associationGeneticsbusiness.industryInsulin sensitivityGenetics/Genomes/Proteomics/Metabolomics11 Medical And Health Sciencesmedicine.diseaseIRS1030104 developmental biologyProto-Oncogene Proteins c-bcl-2Chemokines CCInsulin Receptor Substrate ProteinsFemaleInsulin ResistancebusinessGenome-Wide Association Study
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