0000000000234032

AUTHOR

Richard Henson

0000-0002-0712-2639

showing 2 related works from this author

Physical Activity Predicts Population-Level Age-Related Differences in Frontal White Matter

2018

Physical activity has positive effects on brain health and cognitive function throughout the life span. Thus far, few studies have examined the effects of physical activity on white matter microstructure and psychomotor speed within the same, population-based sample (critical if conclusions are to extend to the wider population). Here, using diffusion tensor imaging and a simple reaction time task within a relatively large population-derived sample (N = 399; 18–87 years) from the Cambridge Centre for Ageing and Neuroscience (Cam-CAN), we demonstrate that physical activity mediates the effect of age on white matter integrity, measured with fractional anisotropy. Higher self-reported daily ph…

AdultMaleAgingmedicine.medical_specialtyExternal capsuleAdolescentPopulationCognitive declineUncinate fasciculusAudiologyCorpus callosumArticle050105 experimental psychologyWhite matter03 medical and health sciencesCognition0302 clinical medicineSurveys and QuestionnairesFractional anisotropyImage Processing Computer-AssistedReaction TimeHumansMedicine0501 psychology and cognitive sciencesCognitive declineeducationExerciseAgedAged 80 and overeducation.field_of_studybusiness.industry05 social sciencesAge FactorsMiddle AgedWhite MatterFrontal LobeDiffusion Magnetic Resonance Imagingmedicine.anatomical_structureEnglandBrain agingAnisotropyFemaleGeriatrics and GerontologybusinessPsychomotor Performance030217 neurology & neurosurgeryDiffusion MRIThe Journals of Gerontology: Series A
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Physical activity predicts population-level age-related differences in frontal white matter

2018

AbstractPhysical activity has positive effects on brain health and cognitive function throughout the lifespan. Thus far, few studies have examined the effects of physical activity on white matter (WM) microstructure and psychomotor speed within the same, population-based sample (critical if conclusions are to extend to the wider population). Here, using diffusion tensor imaging and a simple reaction time task within a relatively large population-derived sample (N = 399; 18–87 years) from the Cambridge Centre for Ageing and Neuroscience (Cam-CAN), we demonstrate that physical activity mediates the effect of age on white matter integrity, measured with fractional anisotropy. Higher self-repor…

medicine.medical_specialtyeducation.field_of_studyInternal capsuleExternal capsulebusiness.industryPopulationUncinate fasciculusAudiologyCorpus callosumWhite mattermedicine.anatomical_structureFractional anisotropymedicineeducationbusinessDiffusion MRI
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