0000000000234500

AUTHOR

Philippe Gros

showing 4 related works from this author

Functional characterization of ORCTL2--an organic cation transporter expressed in the renal proximal tubules.

1998

AbstractChromosome 11p15.5 harbors a gene or genes involved in Beckwith-Wiedemann syndrome that confer(s) susceptibility to Wilms' tumor, rhabdomyosarcoma, and hepatoblastoma. We have previously identified a transcript at 11p15.5 which encodes a putative membrane transport protein, designated organic cation transporter-like 2 (ORCTL2), that shares homology with tetracycline resistance proteins and bacterial multidrug resistance proteins. In this report, we have investigated the transport properties of ORCTL2 and show that this protein can confer resistance to chloroquine and quinidine when overexpressed in bacteria. Immunohistochemistry analyses performed with anti-ORCTL2 polyc.onal antibod…

Beckwith-Wiedemann SyndromeOrganic Cation Transport ProteinsTranscription GeneticMolecular Sequence DataBiophysicsTransfectionBiochemistryHomology (biology)11p15.5Kidney Tubules ProximalStructural BiologyGeneticsmedicineAnimalsHumansMolecular BiologyGeneTetracycline/H+ antiporterKidneyOrganic cation transport proteinsbiologyBacteriaBase SequenceMembrane transport proteinOrganic cation transporterMultidrug resistance-associated protein 2Chromosomes Human Pair 11Tetracycline ResistanceOrganic cation transporter like-2Chromosome MappingMembrane ProteinsBiological TransportChloroquineCell BiologyApical membraneTetracyclineMolecular biologyQuinidineDrug Resistance MultipleRecombinant ProteinsKineticsmedicine.anatomical_structureBiochemistryOligodeoxyribonucleotidesCOS Cellsbiology.proteinImmunohistochemistryCarrier ProteinsFEBS letters
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Biodiversité en environnement marin.

2012

208 pages; National audience

[ SDV.BID ] Life Sciences [q-bio]/Biodiversity[SDV.BID]Life Sciences [q-bio]/BiodiversityComputingMilieux_MISCELLANEOUS[SDV.BID] Life Sciences [q-bio]/Biodiversity
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NHC-Based Iron Sensitizers for DSSCs

2018

International audience; Nanostructured dye-sensitized solar cells (DSSCs) are promising photovoltaic devices because of their low cost and transparency. Ruthenium polypyridine complexes have long been considered as lead sensitizers for DSSCs, allowing them to reach up to 11% conversion efficiency. However, ruthenium suffers from serious drawbacks potentially limiting its widespread applicability, mainly related to its potential toxicity and scarcity. This has motivated continuous research efforts to develop valuable alternatives from cheap earth-abundant metals, and among them, iron is particularly attractive. Making iron complexes applicable in DSSCs is highly challenging due to an ultrafa…

NHC ligands[CHIM.ORGA]Chemical Sciences/Organic chemistry[CHIM.COOR] Chemical Sciences/Coordination chemistry[CHIM.ORGA] Chemical Sciences/Organic chemistrylcsh:QD146-197[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry[CHIM.THEO] Chemical Sciences/Theoretical and/or physical chemistryiron complexes[CHIM] Chemical Scienceslcsh:Inorganic chemistry[CHIM]Chemical Sciences[CHIM.COOR]Chemical Sciences/Coordination chemistryexcited statesCèl·lules fotoelèctriquesphotophysicsFerro
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A Time Projection Chamber with GEM-Based Readout

2016

For the International Large Detector concept at the planned International Linear Collider, the use of time projection chambers (TPC) with micro-pattern gas detector readout as the main tracking detector is investigated. In this paper, results from a prototype TPC, placed in a 1 T solenoidal field and read out with three independent GEM-based readout modules, are reported. The TPC was exposed to a 6 GeV electron beam at the DESY II synchrotron. The efficiency for reconstructing hits, the measurement of the drift velocity, the space point resolution and the control of field inhomogeneities are presented.

Nuclear and High Energy PhysicsDrift velocityPhysics - Instrumentation and DetectorsInternational Linear ColliderMicropattern gaseous detectors (MPGD)Physics::Instrumentation and DetectorsFOS: Physical sciencesTracking (particle physics)01 natural scienceslaw.inventionHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)law[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex]Gas electron multipliers (GEM)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]International Large Detector (ILD)electron: irradiationtracking detector[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Detectors and Experimental Techniques010306 general physicsInstrumentationspatial resolution[ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Physicsmagnetic field: spatial distributionInternational Linear Collider (ILC)Time projection chamber010308 nuclear & particles physicsILD detectorDetectordrift velocityDESYInstrumentation and Detectors (physics.ins-det)Synchrotrontime projection chamberefficiencygas electron multiplierGas electron multiplierPhysics::Accelerator PhysicsHigh Energy Physics::ExperimentTime projection chambers (TPC)
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