0000000000240308

AUTHOR

K. Farrag

showing 3 related works from this author

Involvement of the cholinergic basal forebrain nuclei in spinocerebellar ataxia type 2 (SCA2)

2013

Aims: Spinocerebellar ataxia type 2 (SCA2) belongs to the CAG repeat or polyglutamine diseases. Along with a large variety of motor, behavioural and neuropsychological symptoms the clinical picture of patients suffering from this autosomal dominantly inherited ataxia may also include deficits of attention, impairments of memory, as well as frontal-executive and visuospatial dysfunctions. As the possible morphological correlates of these cognitive SCA2 deficits are unclear we examined the cholinergic basal forebrain nuclei, which are believed to be crucial for several aspects of normal cognition and may contribute to impairments of cognitive functions under pathological conditions. Methods: …

Medial septal nucleusBasal forebrainHistologyAtaxiabusiness.industrySubstantia innominataAnatomymedicine.diseaseDiagonal band of BrocaPathology and Forensic Medicinemedicine.anatomical_structurenervous systemNeurologyPhysiology (medical)medicineSpinocerebellar ataxiaCholinergicNeurology (clinical)medicine.symptomCholinergic neuronbusinessNeuroscienceNeuropathology and Applied Neurobiology
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IceCube-Gen2: The Window to the Extreme Universe

2020

The observation of electromagnetic radiation from radio to $\gamma$-ray wavelengths has provided a wealth of information about the universe. However, at PeV (10$^{15}$ eV) energies and above, most of the universe is impenetrable to photons. New messengers, namely cosmic neutrinos, are needed to explore the most extreme environments of the universe where black holes, neutron stars, and stellar explosions transform gravitational energy into non-thermal cosmic rays. The discovery of cosmic neutrinos with IceCube has opened this new window on the universe. In this white paper, we present an overview of a next-generation instrument, IceCube-Gen2, which will sharpen our understanding of the proce…

PhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)astro-ph.HENuclear and High Energy PhysicsActive galactic nucleus010308 nuclear & particles physicsHigh-energy astronomyGravitational wavemedia_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaAstrophysics::Instrumentation and Methods for AstrophysicsAstronomyFOS: Physical sciencesCosmic ray01 natural sciencesUniverseNeutron star0103 physical sciencesNeutrinoNeutrino astronomyAstrophysics - High Energy Astrophysical Phenomena010303 astronomy & astrophysicsmedia_common
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Combined sensitivity to the neutrino mass ordering with JUNO, the IceCube Upgrade, and PINGU

2020

Physical review / D 101(3), 032006 (1-19) (2020). doi:10.1103/PhysRevD.101.032006

Physics - Instrumentation and DetectorsPhysics::Instrumentation and Detectorsantineutrino/e: energy spectrumJoint analysishiukkasfysiikka7. Clean energy01 natural sciencesString (physics)PINGUHigh Energy Physics - ExperimentSubatomär fysikHigh Energy Physics - Experiment (hep-ex)neutrino: atmosphereSubatomic Physics[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Particle Physics Experimentsneutrino: massphysics.ins-detPhysicsJUNOPhysicsneutriinotoscillation [neutrino]Instrumentation and Detectors (physics.ins-det)massa (fysiikka)atmosphere [neutrino]tensionneutrino: nuclear reactormass difference [neutrino]ddc:UpgradePhysique des particules élémentairesnuclear reactor [neutrino]proposed experimentNeutrinoperformanceParticle physicsAstrophysics::High Energy Astrophysical Phenomenaneutrino: mass differenceFOS: Physical sciencesddc:500.25300103 physical sciencesEnergy spectrumIceCube: upgradeOSCILLATIONSddc:530Sensitivity (control systems)[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsNeutrino oscillationenergy spectrum [antineutrino/e]hep-ex010308 nuclear & particles physicssensitivityPhysics and Astronomymass [neutrino]stringupgrade [IceCube]High Energy Physics::ExperimentReactor neutrinoneutrino: oscillationMATTER
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