0000000000242945

AUTHOR

Frank Biertz

showing 2 related works from this author

The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline

2016

Abstract Background The German COPD cohort study COSYCONET (" CO PD and SY stemic consequences- CO morbidities NET work") investigates the interaction of lung disease, comorbidities and systemic inflammation. Recruitment took place from 2010 to 2013 in 31 study centers. In addition to the baseline visit, follow-up visits are scheduled at 6, 18, 36 and 54 months after baseline. The study also comprises a biobank, image bank, and includes health economic data. Here we describe the study design of COSYCONET and present baseline data of our COPD cohort. Methods Inclusion criteria were broad in order to cover a wide range of patterns of the disease. In each visit, patients undergo a large panel …

SpirometryAdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyComorbiditySeverity of Illness IndexCohort Studies03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineRisk FactorsInternal medicineGermanySeverity of illnessMedicineHumansCOPD030212 general & internal medicineProspective StudiesProspective cohort studyAgedAged 80 and overCOPDmedicine.diagnostic_testSystemic inflammationbusiness.industrySmokingCohortStudy designMiddle Agedmedicine.diseaseComorbiditySystemic Inflammatory Response SyndromeObservational Studies as Topic030228 respiratory systemCohortPhysical therapyDisease ProgressionPopulation studyFemaleCohort ; Comorbidity ; Copd ; Study Design ; Systemic InflammationbusinessCohort studyFollow-Up StudiesRespiratory Medicine
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Relationship between clinical and radiological signs of bronchiectasis in COPD patients: Results from COSYCONET.

2020

Bronchiectasis (BE) might be frequently present in COPD but masked by COPD symptoms. We studied the relationship of clinical signs of bronchiectasis to the presence and extent of its radiological signs in patients of different COPD severity. Visit 4 data (GOLD grades 1-4) of the COSYCONET cohort was used. Chest CT scans were evaluated for bronchiectasis in 6 lobes using a 3-point scale (0: absence, 1: ≤50%, 2: >50% BE-involvement for each lobe). 1176 patients were included (61%male, age 67.3y), among them 38 (3.2%) with reported physicians' diagnosis of bronchiectasis and 76 (6.5%) with alpha1-antitrypsin deficiency (AA1D). CT scans were obtained in 429 patients. Within this group, any sign…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyCopd patientsMedizinComorbiditySeverity of Illness IndexPulmonary Disease Chronic ObstructiveMedicineHumansIn patientLungAgedAged 80 and overCOPDBronchiectasisbusiness.industryPhlegmMiddle Agedmedicine.diseaseBronchiectasisRadiological weaponClinical diagnosisCohortFemaleRadiography ThoracicRadiologymedicine.symptombusinessTomography X-Ray ComputedRespiratory medicine
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