0000000000243026

AUTHOR

Beatriz Rodríguez-iglesias

showing 2 related works from this author

New methods to improve the safety assessment of cryopreserved ovarian tissue for fertility preservation in breast cancer patients

2015

Objective To develop a novel molecular panel of markers to detect breast cancer (BC) disseminated malignant cells in ovarian tissue, and to improve the safety of ovarian tissue transplantation. Design Experimental study. Setting University hospital. Patient(s) Ten ovarian biopsies from healthy patients, 13 biopsies with diagnosed BC metastasis, and 4 biopsies from primary BC tumor for designing a diagnostic panel of BC cell contamination; 60 ovarian biopsies from BC patients undergoing fertility preservation for validating the panel. Animal(s) Female nude mice. Intervention(s) A novel panel for BC malignant cell detection by reverse-transcription polymerase chain reaction (RT-PCR), inmmunoh…

OncologyPathologyBiopsyMetastasisPregnancyRisk FactorsMedicineOvarian tissue cryopreservationFertility preservationMUC1Ovarian Neoplasmsmedicine.diagnostic_testReverse Transcriptase Polymerase Chain ReactionMammaglobin AFertility PreservationObstetrics and GynecologyMiddle AgedImmunohistochemistrymedicine.anatomical_structureNeoplasm MicrometastasisHeterograftsFemaleInfertility FemaleAdultmedicine.medical_specialtyReproductive Techniques AssistedMice NudeBreast NeoplasmsOvaryBreast cancerPredictive Value of TestsInternal medicineBiopsyBiomarkers TumorAnimalsHumansNeoplasm InvasivenessAgedGlycoproteinsCryopreservationbusiness.industryOvaryMucinsMembrane Transport ProteinsReproducibility of Resultsmedicine.diseaseTransplantationFertilityReproductive MedicineCase-Control StudiesCarrier ProteinsbusinessFertility and Sterility
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Development, validation and clinical use of an expanded pan-ethnic preconception carrier genetic screening test in assisted reproductive technology p…

2015

GynecologyGenetic screening testmedicine.medical_specialtyAssisted reproductive technologyReproductive Medicinebusiness.industryFamily medicinemedicine.medical_treatmentEthnic groupObstetrics and GynecologyMedicinebusinessFertility and Sterility
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