0000000000243712
AUTHOR
Santtu Mikkonen
showing 7 related works from this author
A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC stud…
2020
Abstract Aims/hypothesis We studied for the first time the long-term effects of a combined physical activity and dietary intervention on insulin resistance and fasting plasma glucose in a general population of predominantly normal-weight children. Methods We carried out a 2 year non-randomised controlled trial in a population sample of 504 children aged 6–9 years at baseline. The children were allocated to a combined physical activity and dietary intervention group (306 children at baseline, 261 children at 2-year follow-up) or a control group (198 children, 177 children) without blinding. We measured fasting insulin and fasting glucose, calculated HOMA-IR, assessed physical activity and se…
The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study
2020
Funder: Opetus- ja Kulttuuriministeriö; doi: http://dx.doi.org/10.13039/501100003126
The effects of an 8-year individualised lifestyle intervention on food consumption and nutrient intake from childhood to adolescence: the PANIC Study.
2021
Abstract We aimed to investigate the effects of a long-term, individualised, family-based lifestyle intervention on food consumption and nutrient intake from childhood to adolescence. We conducted an 8-year diet and physical activity intervention study in a population sample of children aged 7–9 years at baseline in 2007–2009. We allocated the participants to the intervention group (n 306) and the control group (n 198). We assessed diet by 4-d food records at baseline, 2-year follow-up and 8-year follow-up. We analysed the data using linear mixed-effects models adjusted for age at baseline and sex. The consumption of vegetables and vegetable oil-based spreads (fat ≥60 %) increased in the in…
The role of VOC oxidation products in continental new particle formation
2008
Abstract. Aerosol physical and chemical properties and trace gas concentrations were measured during the QUEST field campaign in March–April, 2003, in Hyytiälä, Finland. Our aim was to understand the role of oxidation products of VOC's such as mono- and sesquiterpenes in atmospheric nucleation events. Particle chemical compositions were measured using the Aerodyne Aerosol Mass Spectrometer, and chemical compositions of aerosol samples collected with low-pressure impactors and a high volume sampler were analysed using a number of techniques. The results indicate that during and after new particle formation, all particles larger than 50 nm in diameter contained similar organic substances that…
Modeling atmospheric aging of small-scale wood combustion emissions: distinguishing causal effects from non-causal associations
2022
Small-scale wood combustion is a significant source of particulate emissions. Atmospheric transformation of wood combustion emissions is a complex process involving multiple compounds interacting simultaneously. Thus, an advanced methodology is needed to study the process in order to gain a deeper understanding of the emissions. In this study, we are introducing a methodology for simplifying this complex process by detecting dependencies of observed compounds based on a measured dataset. A statistical model was fitted to describe the evolution of combustion emissions with a system of differential equations derived from the measured data. The performance of the model was evaluated using simu…
Atmospheric aging of small-scale wood combustion emissions (model MECHA 1.0) – is it possible to distinguish causal effects from non-causal ass…
2020
Abstract. Primary emissions of wood combustion are complex mixtures of hundreds or even over a thousand compounds, which pass through a series of chemical reactions and physical transformation processes in the atmosphere (aging). This aging process depends on atmospheric conditions, such as concentration of atmospheric oxidizing agents (OH radical, ozone and nitrate radicals), humidity and solar radiation, and is known to strongly affect the characteristics of atmospheric aerosols. However, there are only few models that are able to represent the aging of emissions during its lifetime in the atmosphere. In this work, we implemented a model (Model for aging of Emissions in environmental CHAm…
Codes and datasets related to https://doi.org/10.5194/gmd-2020-13
2020
Codes and datasets related to https://doi.org/10.5194/gmd-2020-13, discussion paper.