0000000000246625
AUTHOR
Agnès Fromont
Coûts de la sclérose en plaques en France
Multiple sclerosis (MS) is one of the 30 chronic conditions specifically listed by the French healthcare system as a long-term disease (affections de longue duree [ALD]) for which the main health insurance fund (Caisse nationale d'assurance maladie des travailleurs salaries [CNAMTS]) provides full (100%) coverage of healthcare costs. The CNAMTS insures 87% of the French population (52,359,912 of the 60,028,292 inhabitants). The objectives of this study were to evaluate the direct and indirect medical costs of MS among the entire population insured by the CNAMTS in France in 2004. The CNAMTS provided us with access to the ALD database of patients with MS that contains different MS-related ex…
High efficiency and clinical relevance of exome sequencing in the daily practice of neurogenetics
ObjectiveTo assess the efficiency and relevance of clinical exome sequencing (cES) as a first-tier or second-tier test for the diagnosis of progressive neurological disorders in the daily practice of Neurology and Genetic Departments.MethodsSixty-seven probands with various progressive neurological disorders (cerebellar ataxias, neuromuscular disorders, spastic paraplegias, movement disorders and individuals with complex phenotypes labelled ‘other’) were recruited over a 4-year period regardless of their age, gender, familial history and clinical framework. Individuals could have had prior genetic tests as long as it was not cES. cES was performed in a proband-only (60/67) or trio (7/67) st…
Interférences des traitements par biotine avec les immunodosages : il est temps de trouver une solution à long terme !
La Presse Medicale - In Press.Proof corrected by the author Available online since vendredi 22 decembre 2017
Profil de qualité de vie subjective chez les sujets atteints de sclérose en plaques
Resume Objectifs Cette etude evalue la qualite de vie subjective chez des personnes atteintes de sclerose en plaques (SEP) en tenant compte des criteres de satisfaction et d’importance accordee a differents domaines de vie. Methode Soixante et un sujets atteints de SEP de forme remittente et progressive ont participe a une evaluation psychologique comprenant un entretien et trois questionnaires : le profil de qualite de vie subjective (PQVS), l’inventaire d’anxiete Trait-Etat (STAI) et l’inventaire de depression de Beck (BDI). Resultats Les resultats montrent un niveau bas de satisfaction generale de la qualite de vie subjective. La fatigue et la douleur sont les domaines de vie les plus in…