Assessing complexity and causality in heart period variability through a model-free data-driven multivariate approach

The aim of this study is to emphasize the importance of model-free data-driven mul- tivariate approaches in describing HP variability and cardiovascular control mechanisms responsible for inducing HP changes via modifications of different cardiovascular vari- ables such as SAP and RESP. The goal was achieved through the application, a previously proposed model-free data-driven multivariate framework devised to assess complexity and causality over a multivariate set composed by several, simultaneously recorded, car- diovascular variability series (Porta et al., 2014). The approach was applied to assess the complexity of the cardiac control, through the evaluation of the amount of irregularit…

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