0000000000248944

AUTHOR

Thomas Horvatits

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Hepatitis E seroprevalence and viremia rate in immunocompromised patients: a systematic review and meta‐analysis

2020

Background and aims Hepatitis E is an infectious disease of the liver caused by the hepatitis E virus (HEV). Immunocompromised patients present a particular risk group, as chronification of hepatitis E leading to life-threatening cirrhosis occurs when these patients are infected. Therefore, this study aims to estimate and compare the anti-HEV seroprevalence and the rate of HEV RNA positivity in transplant recipients and patients with human immunodeficiency virus (HIV). Methods This systematic review and meta-analysis involved a literature search (PubMed, Scopus; 1,138 studies) including 120 studies from 1996 to 2019, reporting anti-HEV seroprevalence and/or HEV-RNA positivity. Statistical a…

medicine.medical_specialtyCirrhosisHIV InfectionsViremiamedicine.disease_causeImmunocompromised Host03 medical and health sciences0302 clinical medicineHepatitis E virusSeroepidemiologic StudiesInternal medicineHepatitis E virusmedicineHumansSeroprevalenceHepatitis AntibodiesViremiaHepatologybusiness.industryvirus diseasesmedicine.diseaseHepatitis EHepatitis ETransplantationChronic infectionImmunoglobulin G030220 oncology & carcinogenesisMeta-analysisRNA Viral030211 gastroenterology & hepatologybusinessLiver International
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