0000000000249528
AUTHOR
Lucienne Juillerat-jeanneret
Tumour-derived and host-derived nitric oxide differentially regulate breast carcinoma metastasis to the lungs.
To study the role of nitric oxide (NO) in lung metastasis of breast carcinoma, we isolated two cell clones (H and J) from the parental EMT-6 murine breast carcinoma cell line, based on their differential NO production. In vitro, EMT-6 J cells, but not EMT-6H cells, constitutively expressed inducible NO synthase (NOS II) and secreted high levels of NO. IL-1beta increased NO production in both clones, and TNF-alpha had a synergistic effect on IL-1beta-induced NO production, but NO production by EMT-6 J cells was always higher than by EMT-6H cells. Proliferation, survival and adhesion to lung-derived endothelial cells of both clones were similar and were not affected by NO. In vivo, both clone…
Catalytic and anticancer activities of sawhorse-type diruthenium tetracarbonyl complexes derived from fluorinated fatty acids
The reaction of fluorinated fatty acids, perfluorobutyric acid (C3F7CO2H), and perfluorododecanoic acid (C11F23CO2H), with dodecacarbonyltriruthenium (Ru3(CO)12) under reflux in tetrahydrofuran, followed by addition of two-electron donors (L) such as pyridine, 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane, or triphenylphosphine, gives stable diruthenium complexes Ru2(CO)4(μ2-η2-O2CC3F7)2(L)2 (1a, L = C5H5N; 1b, L = PTA; 1c, L = PPh3) and Ru2(CO)4(μ2-η2-O2CC11F23)2(L)2 (2a, L = C5H5N; 2b, L = PTA; 2c, L = PPh3). The catalytic activity of the complexes for hydrogenation of styrene under supercritical carbon dioxide has been assessed and compared to the analogous triphenylphosphine complexes w…
Autophagy
Klionsky, Daniel J. et al.
CCDC 914515: Experimental Crystal Structure Determination
Related Article: Justin P. Johnpeter, Laurent Plasseraud, Frédéric Schmitt, Lucienne Juillerat-Jeanneret, Bruno Therrien|2013|J.Coord.Chem.|66|1753|doi:10.1080/00958972.2013.790020
CCDC 914514: Experimental Crystal Structure Determination
Related Article: Justin P. Johnpeter, Laurent Plasseraud, Frédéric Schmitt, Lucienne Juillerat-Jeanneret, Bruno Therrien|2013|J.Coord.Chem.|66|1753|doi:10.1080/00958972.2013.790020