0000000000249558

AUTHOR

R. Pio

showing 3 related works from this author

Effects of omalizumab in severe asthmatics across ages: A real life Italian experience

2016

Background This retrospective study aimed at evaluating long-term effects of Omalizumab in elderly asthmatics in a real-life setting. Methods 105 consecutive severe asthmatics (GINA step 4–5; mean FEV1% predicted:66 ± 15.7) treated with Omalizumab for at least 1 year (treatment mean duration 35.1 ± 21.7 months) were divided into 3 groups according to their age at Omalizumab treatment onset: 18–39, 40–64 and ≥ 65 years. Results Comorbidities, number of overweight/obese subjects and patients with late-onset asthma were more frequent among older people. A similar reduction of inhaled corticosteroids dosage and SABA on-demand therapy was observed in all groups during Omalizumab treatment; a sim…

MaleSevere asthmaPediatricsComorbidityOmalizumabOmalizumabOverweightImmunoglobulin ESeverity of Illness IndexElderly0302 clinical medicineAdrenal Cortex HormonesForced Expiratory VolumeAge effectAnti-Asthmatic Agentsasthma allergy elderly omalizumab030212 general & internal medicineYoung adultbiologyReal-lifeAdrenergic beta-AgonistsMiddle AgedTreatment OutcomeItalyFemalemedicine.symptommedicine.drugAdultPulmonary and Respiratory Medicineage effect; elderly; omalizumab; real-life; severe asthmamedicine.medical_specialtyAdolescentSettore MED/10 - Malattie Dell'Apparato RespiratorioAntibodies Monoclonal HumanizedYoung Adult03 medical and health sciencesAge effect; Elderly; Omalizumab; Real-life; Severe asthma; Pulmonary and Respiratory MedicineAdministration InhalationSeverity of illnessmedicineHumansAgedRetrospective StudiesAsthmabusiness.industryRetrospective cohort studyImmunoglobulin Easthmaallergymedicine.diseaseComorbidity030228 respiratory systembiology.proteinbusinessRespiratory Medicine
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Cypress pollen: An unexpected major sensitizing agent in different regions of Italy

2014

In this multicenter survey, we assessed the impact of sensitization to cypress in atopic patients in Italy and determined whether cypress pollen concentration changed over time.Allergists were required to collect the results of 100-200 consecutive skin prick tests (SPTs) performed during 2012. Seasonal symptoms were also recorded, as were airborne cypress pollen concentrations (data from the Italian Aerobiology Association) in 1998-2000 and 2010-2012.We examined 2258 atopic outpatients (56% females; age, 2-84 years) sensitized to at least 1 of the aeroallergens tested (Dermatophagoides species, grass, pellitory, olive, cypress, birch, Alternaria tenuis, and dog and cat dander). We found tha…

CupressuAdultHypersensitivity ImmediateMaleAdolescentSettore MED/10 - Malattie Dell'Apparato RespiratorioSensitizationYoung AdultHypersensitivityHumansChildAgedAged 80 and overAllergenRespiratory allergy; Cypress; Sensitization; Skin prick tests; allergyCypressAllergensCupressusMiddle AgedRespiratory allergyallergyYoung Adult; Humans; Aged; Child; Pollen; Italy; Child Preschool; Hypersensitivity; Aged 80 and over; Allergens; Adult; Hypersensitivity Immediate; Middle Aged; Adolescent; Cupressus; Male; FemaleItalyChild PreschoolSkin prick testsPollenFemaleHuman
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Allergic sensitization to common pets (cats/dogs) according to different possible modalities of exposure: an Italian Multicenter Study

2018

Abstract Background The query “are there animals at home?” is usually administered for collecting information on anamnesis. This modality to consider exposure to pet allergens constitutes a potential bias in epidemiological studies and in clinical practice. The aim of our study was to evaluate/quantify different modalities of exposure to cat/dog in inducing allergic sensitization. Methods Thirty Italian Allergy units participated in this study. Each centre was required to collect the data of at least 20 consecutive outpatients sensitized to cat/dog allergens. A standardized form reported all demographic data and a particular attention was paid in relieving possible modalities of exposure to…

lcsh:Immunologic diseases. AllergyAllergymedicine.medical_specialtyImmunologySettore MED/10 - Malattie Dell'Apparato RespiratorioPets exposureAllergic rhinitisAllergic sensitization03 medical and health sciences0302 clinical medicineInternal medicineEpidemiologyAllergic rhinitiDogHypersensitivitymedicineImmunology and Allergy030212 general & internal medicineAllergic rhinitis Allergic sensitization Bronchial asthma Cat; Dog Hypersensitivity Pets Pets exposure Immunology and Allergy Immunology Molecular BiologyBronchial asthmaMolecular BiologyAllergic rhinitis; Allergic sensitization; Bronchial asthma; Cat; Dog; Hypersensitivity; Pets; Pets exposureAllergic sensitizationAnamnesisCATSModalitiesbusiness.industryResearchCatPetsmedicine.diseasePet ownershipPet030228 respiratory systemMulticenter studyAllergic rhinitis; Allergic sensitization; Bronchial asthma; Cat; Dog; Hypersensitivity; Pets; Pets exposure; Immunology and Allergy; Immunology; Molecular Biologylcsh:RC581-607businessClinical and Molecular Allergy
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