0000000000255440

AUTHOR

José María Vila-vives

showing 2 related works from this author

Effect of Antiangeogenic Treatment on Peritoneal Endometriosis-Associated Nerve Fibers

2013

Pathologymedicine.medical_specialtybusiness.industrymedicineEndometriosisObstetrics and GynecologyGeneral Medicinebusinessmedicine.diseaseObstetrical & Gynecological Survey
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Effect of antiangiogenic treatment on peritoneal endometriosis-associated nerve fibers

2012

Objective To investigate the effect of antiangiogenic treatment on experimental endometriotic lesion nerve fibers. Design Heterologous mouse model of endometriosis. Setting University Institute IVI, University Hospital La Fe. Animal(s) Ovariectomized nude mice (n = 16) receiving human endometrial fragments from oocyte donors (n = 4). Intervention(s) Endometrium fragments stuck in the peritoneum of 5-week-old female nude mice treated with vehicle (n = 8) and antiangiogenic agent cabergoline (n = 8; Cb 2, 0.05 mg/kg/day) for 14 days. Main Outcome Measure(s) Immunofluorescence analysis of von-Willebrand factor (vWF) and vascular smooth muscle cells (αSMA) for evaluating the number of immature …

Pathologymedicine.medical_specialtyCabergolineTime FactorsAngiogenesisOvariectomyEndometriosisEndometriosisFluorescent Antibody TechniqueMice NudeAngiogenesis InhibitorsNerve fiberPeritoneal DiseasesEndometriumEndometriumMicechemistry.chemical_compoundNerve FibersPeritoneumvon Willebrand FactorAnimalsHumansMedicineMast CellsErgolinesNeovascularization Pathologicbusiness.industryMacrophagesObstetrics and GynecologyMast cellmedicine.diseaseImmunohistochemistryActinsVascular endothelial growth factorDisease Models Animalmedicine.anatomical_structureReproductive MedicinechemistryMicrovesselsImmunologyFemalebusinessBiomarkersBlood vesselFertility and Sterility
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