0000000000258414

AUTHOR

Marcello Migliore

showing 4 related works from this author

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

2023

Background: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods: This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, r…

general surgeryacute care surgerySettore MED/18 - CHIRURGIA GENERALEclimate change; trauma; general surgery; acute care surgerySettore MED/40 - Ginecologia E Ostetriciaenvironmental impactsurgerySettore MED/31 - Otorinolaringoiatriaclimate changetraumaNoneMedicine and Health SciencesSurgeryoperating theatreenvironment
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Early effects of fluoro-edenite: correlation between IL-18 serum levels and pleural and parenchymal abnormalities.

2016

Fluoro-edenite (FE) is a natural mineral asbestos-like fibrous species first isolated in Biancavilla, Sicily. In order to clarify potential involvement of IL-18 in the pathogenesis of FE-induced chest abnormalities, we analyzed IL-18 serum levels in FE-exposed workers (FEEW) and correlated them with pleural and parenchymal abnormalities. A total of 21 FEEWs, residing in Biancavilla for >30 years, with a working seniority of 17 ± 6.1 years were examined. High-resolution computed tomography scans revealed low grade of fibrosis in 8 (38%) FEEWs, and pleural plaques (PPs) in 13 (62%) FEEWs. The mean IL-18 level was 203.13 ± 90.43 pg/ml. Pearson correlation showed a significant association (…

0301 basic medicineAdultMaleCancer ResearchPathologymedicine.medical_specialtyFluoro-edeniteComputed tomographyNatural mineralPathogenesis03 medical and health sciences0302 clinical medicineFibrosisRisk FactorsOccupational ExposureParenchymamedicineHumansIL-18; asbestos; natural carcinogenic fibermedicine.diagnostic_testbusiness.industryAsbestos AmphiboleInterleukin-18General MedicineMiddle AgedPleural Diseasesmedicine.diseaseRespiratory Function Tests030104 developmental biologyOncology030220 oncology & carcinogenesisInterleukin 18FemalebusinessLung Diseases InterstitialTomography Spiral ComputedIL-18
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Wider implications of video-assisted thoracic surgery versus open approach for lung metastasectomy

2015

ABSTRACT  Lung metastasectomy is considered a safe and potentially curative procedure despite there is not a strong evidence that metastasectomy prolongs long-term survival in patients with lung metastases. Moreover, the debate is open regarding the best approach for lung metastasectomy, video-assisted thoracic surgery versus open approach. A systematic review of literature to clarify what is the best approach to prolong survival in patients with lung metastases was performed. Our study confirms that overall survival is equivalent for video-assisted thoracic surgery and thoracotomy, therefore the ‘gold standard’ surgical treatment for lung metastases remains a point of debate. The choice o…

Cancer Researchmedicine.medical_specialtyLung Neoplasmslung metastasectomymedicine.medical_treatmentSettore MED/21 - Chirurgia ToracicaSingle Centersurvivallunglaw.inventionRandomized controlled triallawmedicineHumanspulmonary metastasesThoracotomyLungThoracic Surgery Video-Assistedbusiness.industryGeneral surgeryGold standardgold standardMetastasectomyGeneral Medicinegold standard lung lung metastasectomy pulmonary metastases survival thoracotomy VATS video-assisted thoracic surgerygold standard; lung; lung metastasectomy; pulmonary metastases; survival; thoracotomySurgerymedicine.anatomical_structureThoracotomyOncologyCardiothoracic surgeryVideo assisted thoracic surgeryMetastasectomybusiness
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Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 count…

2022

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planning. This study aimed to develop and validate a novel index to support local elective surgical system strengthening and address growing backlogs. Methods: First, we performed an international consultation through a four-stage consensus process to develop a multidomain index for hospital-level assess…

MaleHealth system resilience.*COVID-19/epidemiologySocial SciencesSağlık BilimleriGlobal HealthFundamental Medical SciencesClinical Medicine (MED)AnaesthesiasurgeryTIP GENEL & DAHİLİnisu navedene ključne riječiElective backlogMedicine and Health SciencesTOOLKlinik Tıp (MED)610 Medicine & healthMEDICINE GENERAL & INTERNAL11 Medical and Health SciencesKlinik Tıpsurgery; global surgery; health-care systemCovid19NIHR Global Health Unit on Global SurgeryGeneral MedicineHospitalsHospital preparedneTıphealth-care systemElective Surgical ProceduresHEALTH SYSTEMS*PandemicsMedicineFemaleLife Sciences & BiomedicineHumanHälso- och sjukvårdsorganisation hälsopolitik och hälsoekonomiTemel Tıp Bilimleri610 Medicine & healthglobal surgeryGenel TıpCAPACITYCOVIDSurg CollaborativeHospitalMedicine General & InternalGeneral & Internal MedicineHealth SciencesHumansPandemicsScience & TechnologyElective Surgical ProcedurePandemicKirurgiPlanned surgeryCOVID-19Health Care Service and Management Health Policy and Services and Health EconomyCLINICAL MEDICINESettore MED/18Settore MED/18 - Chirurgia Generaleelective surgeryHospital assessmentSystems strengtheningSurgeryHuman medicineMETHODOLOGY[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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