0000000000261194

AUTHOR

Emmanouil Vardas

showing 3 related works from this author

Diagnostic challenges in a diffuse large B-cell lymphoma of the maxilla presenting as exposed necrotic bone

2022

Lymphoma is the second most common malignancy in the head and neck area, affecting both nodal and extranodal sites, including oral soft and hard tissues, usually in the form of non-Hodgkin's lymphoma (NHL). However, lymphomas of the jaws, including diffuse large B-cell lymphoma (DLBCL), the most common type of NHL, are very rare and may cause significant diagnostic challenges resembling common jaw pathologies, such as periapical lesions, osteomyelitis and osteonecrosis. The aim of this paper is to present a rare case of DLBCL in an 84-years-old diabetic male patient on methylprednisolone treatment for autoimmune hemolytic anemia. The lesion appeared clinically as exposed necrotic bone of th…

immune system diseaseshemic and lymphatic diseasesGeneral DentistryUNESCO:CIENCIAS MÉDICASJournal of clinical and experimental dentistry
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Osteonecrosis of the jaw related to non-antiresorptive medications: a systematic review

2018

The reporting of osteonecrosis of the jaw (ONJ) related to anticancer agents without known antiresorptive properties (non-antiresorptives), such as antiangiogenics, tyrosine kinase inhibitors, mammalian target of rapamycin inhibitors, immune checkpoint inhibitors, and cytotoxic chemotherapy is increasing. To review characteristics of ONJ in cancer patients receiving non-antiresorptives. A systematic review of the literature between 2009 and 2017 was conducted by the Bone Study Group of MASCC/ISOO. Of 6249 articles reviewed and from personal communication, 42 ONJ cases related to non-antiresorptives were identified. No gender predilection was noted. Median age was 60 years and ONJ stage 2 wa…

AdultMaleOncologyBRAF inhibitormedicine.medical_specialtymTOR inhibitorsImmune checkpoint inhibitorsInhibitors of angiogenesiTyrosine kinase inhibitorBone resorptionImmune checkpoint inhibitorDelayed diagnosisCytotoxic chemotherapyBone resorption03 medical and health sciences0302 clinical medicineProstateInternal medicinemedicineHumans030212 general & internal medicineStage (cooking)AgedBone Density Conservation AgentsDiphosphonatesOsteonecrosis of the jawbusiness.industryOsteonecrosisCancerMiddle AgedCytotoxic chemotherapymedicine.diseasemedicine.anatomical_structureJawOncology030220 oncology & carcinogenesisBisphosphonate-Associated Osteonecrosis of the JawFemaleOsteonecrosis of the jawbusiness
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Orthodontic treatment as triggering factor of Medication Related Osteonecrosis of the Jaw in a breast cancer patient. Report of a rare case

2023

Orthodontic treatment in adult patient is widely accepted nowadays. Therefore, orthodontists are needed to interact with more complex medical histories that may interfere with the orthodontic treatment. Antiresorptive medication is a widely used treatment

General DentistryUNESCO:CIENCIAS MÉDICASJournal of Clinical and Experimental Dentistry
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