0000000000261541

AUTHOR

Maria Dusinska

showing 2 related works from this author

Versailles project on advanced materials and standards (VAMAS) interlaboratory study on measuring the number concentration of colloidal gold nanopart…

2022

The advancement of analytical methods for nanoparticle measurements is critical both for the growing industrial exploitation of engineered nanoparticles and for developing robust strategies to understand and control the concentration of nanomaterials in humans and the environment. For high value nanoparticles, the measurement of nanoparticle number concentration in a liquid directly impacts the ability to assess the scale and reproducibility of the production process, it allows optimisation of efficiency and supports regulatory compliance. This measurement is also useful to monitor and control the intentional or accidental release of engineered nanoparticles into the environment at the produc…

TechnologyconcentrationkolloiditChemistry MultidisciplinaryMaterials ScienceMaterials Science MultidisciplinaryPLASMA-MASS SPECTROMETRYkultaPhysics Appliedcolloids10 TechnologySIZE DISTRIBUTIONSCATTERINGLife ScienceGeneral Materials ScienceNanoscience & NanotechnologyTeam Organic ContaminantsScience & Technology02 Physical SciencesPhysicsNanostructured materialsQUANTIFICATIONgoldmittaustekniikkaChemistrylaboratoriotekniikkapitoisuusColloidal goldPhysical SciencesScience & Technology - Other TopicsNanoparticlesnanohiukkasetPARTICLE03 Chemical Sciences
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Inter-laboratory validation of procedures for measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2’-deoxyguanosine in DNA.

2002

The aim of ESCODD, a European Commission funded Concerted Action, is to improve the precision and accuracy of methods for measuring 8-oxo-7,8-dihydroguanine (8-oxoGua) or the nucleoside (8-oxodG). On two occasions, participating laboratories received samples of different concentrations of 8-oxodG for analysis. About half the results returned (for 8-oxodG) were within 20% of the median values. Coefficients of variation (for three identical samples) were commonly around 10%. A sample of calf thymus DNA was sent, dry, to all laboratories. Analysis of 8-oxoGua/8-oxodG in this sample was a test of hydrolysis methods. Almost half the reported results were within 20% of the median value, and half …

GuanineAnalytical chemistryTest sensitivityThymus GlandSensitivity and SpecificityBiochemistryGas Chromatography-Mass SpectrometryMass SpectrometryOxidative dna damagechemistry.chemical_compound8 oxo 7 8 dihydroguanineAnimalsHumansEuropean commissionInter-laboratoryChromatography High Pressure LiquidChromatographyChemistry8 oxo 7 8 dihydro 2 deoxyguanosineDNAGeneral MedicineCattleBiomarkersDNAChromatography LiquidDNA Damage
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