0000000000262769

AUTHOR

M. Menozzi

showing 2 related works from this author

Burden of Disease in PWH Harboring a Multidrug-Resistant Virus: Data from the PRESTIGIO Registry

2020

AbstractBackgroundCurrently, no data are available on the burden of morbidity and mortality in people with HIV-1 (PWH) harboring a 4-class drug-resistant (4DR) virus (nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase strand transfer inhibitors). The study aimed to assess the incidence of clinical events and death in this population.MethodsThis was a cohort study on PWH from the PRESTIGIO Registry with a documented 4DR virus. Burden of disease was defined as the occurrence of any new event including an AIDS-defining event (ADE) or non-AIDS-defining event (NADE) or death from any cause after 4DR evidence (baseline). Co…

0301 basic medicinemedicine.medical_specialty4-class drug resistance; AIDS-defining event; cancer; death; non-AIDS-defining event4-class drug resistancenon-AIDS-defining event.PopulationMajor ArticlesSettore MED/0703 medical and health sciences0302 clinical medicineInterquartile rangeInternal medicinedeathmedicinecancerCumulative incidenceAIDS-defining event030212 general & internal medicineeducationnon-AIDS-defining eventDisease burdeneducation.field_of_studyProportional hazards modelbusiness.industryIncidence (epidemiology)Hazard ratio030112 virologyAcademicSubjects/MED00290Infectious DiseasesOncologybusinessCohort study
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Validation of lung densitometry threshold at CT for the distinction between senile lung and emphysema in elderly subjects

2015

Background and Aims. An ageing lung is characterised by distal airspace enlargement without alveolar wall destruction: therefore the anatomical distinction between senile lung and emphysema is clear-cut. In clinical settings the definition of precise boundaries between normalcy and pathology is more difficult with the risk of overdiagnosis. CT is an important diagnostic advancement in the field of COPD. Most methods for the evaluation of emphysema are based on the detection and measurement of areas characterised by a density level below a threshold assumed to characterize parenchymal destruction. Methods. Our retrospective study included 47 healthy subjects (65-91 years), 36 never smokers a…

MalePulmonary and Respiratory MedicineAgingmedicine.medical_specialtyCoefficient of variationlcsh:MedicineRespiratory physiologySettore MED/10 - Malattie Dell'Apparato RespiratorioAbsorptiometry PhotonLung densitometry CTsenile lung emphysemaImage Processing Computer-AssistedmedicineHumansSenile lungOverdiagnosisLungAgedAged 80 and overEmphysemaCOPDLungbusiness.industrylcsh:RRetrospective cohort studymedicine.diseaseSurgeryrespiratory tract diseasesAgeingmedicine.anatomical_structurePulmonary EmphysemaDensity distributionRadiologyCardiology and Cardiovascular MedicinebusinessDensitometryTomography Spiral ComputedAlgorithmsCTDensitometryMonaldi Archives for Chest Disease
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