0000000000267832

AUTHOR

A. Barreiro-gonzález

showing 2 related works from this author

Design and Validation of an Expanded Disability Status Scale Model in Multiple Sclerosis.

2020

<b><i>Introduction:</i></b> We aimed to develop and validate an Expanded Disability Status Scale (EDSS) model through clinical, optical coherence tomography (OCT), and magnetic resonance imaging (MRI) measures. <b><i>Methods:</i></b> Sixty-four multiple sclerosis (MS) patients underwent peripapillary retinal nerve fiber layer and segmented macular layers evaluation through OCT (Spectralis, Heidelberg Engineering). Brain parenchymal fraction was quantified through Freesurfer, while cervical spinal cord (SC) volume was assessed manually guided by Spinal Cord Toolbox software analysis. EDSS, neuroradiological, and OCT assessment were carried out …

medicine.medical_specialtyMultiple Sclerosisgenetic structuresPhysics::Medical PhysicsNerve fiber layerOrdinal regressionRetinaExpanded disability status scale Magnetic resonance imaging Multiple sclerosis Spectral domain optical coherence tomography Spinal cordDisability EvaluationOptical coherence tomographyOphthalmologyHumansMedicineCutoffExpanded Disability Status Scalemedicine.diagnostic_testbusiness.industryMultiple sclerosisBrainMagnetic resonance imagingmedicine.diseaseSpinal cordMagnetic Resonance Imagingeye diseasesmedicine.anatomical_structureNeurologyNeurology (clinical)sense organsbusinessTomography Optical Coherence
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Magnetic resonance imaging and optical coherence tomography correlations in multiple sclerosis beyond anatomical landmarks.

2020

Abstract Objective To investigate multiple sclerosis (MS) optical coherence tomography (OCT) cross-sectional correlations with central nervous system (CNS) magnetic resonance imaging (MRI). Material and methods Peripapillary retinal nerve fiber layer (pRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner (INL) and outer nuclear layer (ONL) of 54 relapsing remitting (RRMS) and 38 progressive (PMS, 9 primary and 29 secondary) patients were measured. With less than 3 months brain parenchymal fraction (BPF), spinal cord (SC), total gray matter (GM) and white matter volumes were calculated. Demographical and clinical data was compared according to the history of optic neuritis (H…

Retinal Ganglion Cellsmedicine.medical_specialtyMultiple SclerosisNerve fiber layerWhite matter03 medical and health sciences0302 clinical medicineOptical coherence tomographyOphthalmologymedicineHumansOptic neuritis030212 general & internal medicineOuter nuclear layermedicine.diagnostic_testbusiness.industryMultiple sclerosisMagnetic resonance imagingmedicine.diseaseSpinal cordMagnetic Resonance Imagingmedicine.anatomical_structureCross-Sectional StudiesNeurologysense organsNeurology (clinical)business030217 neurology & neurosurgeryTomography Optical CoherenceJournal of the neurological sciences
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