0000000000267835

AUTHOR

Joan Carreres-polo

showing 3 related works from this author

Design and Validation of an Expanded Disability Status Scale Model in Multiple Sclerosis.

2020

<b><i>Introduction:</i></b> We aimed to develop and validate an Expanded Disability Status Scale (EDSS) model through clinical, optical coherence tomography (OCT), and magnetic resonance imaging (MRI) measures. <b><i>Methods:</i></b> Sixty-four multiple sclerosis (MS) patients underwent peripapillary retinal nerve fiber layer and segmented macular layers evaluation through OCT (Spectralis, Heidelberg Engineering). Brain parenchymal fraction was quantified through Freesurfer, while cervical spinal cord (SC) volume was assessed manually guided by Spinal Cord Toolbox software analysis. EDSS, neuroradiological, and OCT assessment were carried out …

medicine.medical_specialtyMultiple Sclerosisgenetic structuresPhysics::Medical PhysicsNerve fiber layerOrdinal regressionRetinaExpanded disability status scale Magnetic resonance imaging Multiple sclerosis Spectral domain optical coherence tomography Spinal cordDisability EvaluationOptical coherence tomographyOphthalmologyHumansMedicineCutoffExpanded Disability Status Scalemedicine.diagnostic_testbusiness.industryMultiple sclerosisBrainMagnetic resonance imagingmedicine.diseaseSpinal cordMagnetic Resonance Imagingeye diseasesmedicine.anatomical_structureNeurologyNeurology (clinical)sense organsbusinessTomography Optical Coherence
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Deciphering Multiple Sclerosis Progression

2021

Esclerosi múltiple; Neurodegeneració Esclerosis múltiple; Neurodegeneración Multiple sclerosis; Nneurodegeneration Multiple sclerosis (MS) is primarily an inflammatory and degenerative disease of the central nervous system, triggered by unknown environmental factors in patients with predisposing genetic risk profiles. The prevention of neurological disability is one of the essential goals to be achieved in a patient with MS. However, the pathogenic mechanisms driving the progressive phase of the disease remain unknown. It was described that the pathophysiological mechanisms associated with disease progression are present from disease onset. In daily practice, there is a lack of clinical, ra…

Oncologymedicine.medical_specialty:Other subheadings::Other subheadings::/physiopathology [Other subheadings]:Otros calificadores::Otros calificadores::/fisiopatología [Otros calificadores]Esclerosi múltiple - Propensió:Genetic Phenomena::Genotype::Genetic Predisposition to Disease [PHENOMENA AND PROCESSES]ReviewDiseaseneurofilamentEsclerosi múltiple - Fisiologia patològicamultiple sclerosislcsh:RC346-429Sistema nerviós - Degeneració03 medical and health sciences0302 clinical medicineDegenerative diseaseInternal medicinemedicineIn patient030212 general & internal medicine:enfermedades del sistema nervioso::enfermedades neurodegenerativas [ENFERMEDADES]lcsh:Neurology. Diseases of the nervous system:fenómenos genéticos::genotipo::predisposición genética a la enfermedad [FENÓMENOS Y PROCESOS]Expanded Disability Status Scalebusiness.industryMultiple sclerosisNeurodegenerationDisease progressionneurodegeneration:Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases CNS::Multiple Sclerosis [DISEASES]medicine.diseaseClinical trialprogressive multiple sclerosisNeurology:Nervous System Diseases::Neurodegenerative Diseases [DISEASES]:enfermedades del sistema nervioso::enfermedades autoinmunitarias del sistema nervioso::enfermedades autoinmunes desmielinizantes del SNC::esclerosis múltiple [ENFERMEDADES]Neurology (clinical)business030217 neurology & neurosurgeryMRI
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Magnetic resonance imaging and optical coherence tomography correlations in multiple sclerosis beyond anatomical landmarks.

2020

Abstract Objective To investigate multiple sclerosis (MS) optical coherence tomography (OCT) cross-sectional correlations with central nervous system (CNS) magnetic resonance imaging (MRI). Material and methods Peripapillary retinal nerve fiber layer (pRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner (INL) and outer nuclear layer (ONL) of 54 relapsing remitting (RRMS) and 38 progressive (PMS, 9 primary and 29 secondary) patients were measured. With less than 3 months brain parenchymal fraction (BPF), spinal cord (SC), total gray matter (GM) and white matter volumes were calculated. Demographical and clinical data was compared according to the history of optic neuritis (H…

Retinal Ganglion Cellsmedicine.medical_specialtyMultiple SclerosisNerve fiber layerWhite matter03 medical and health sciences0302 clinical medicineOptical coherence tomographyOphthalmologymedicineHumansOptic neuritis030212 general & internal medicineOuter nuclear layermedicine.diagnostic_testbusiness.industryMultiple sclerosisMagnetic resonance imagingmedicine.diseaseSpinal cordMagnetic Resonance Imagingmedicine.anatomical_structureCross-Sectional StudiesNeurologysense organsNeurology (clinical)business030217 neurology & neurosurgeryTomography Optical CoherenceJournal of the neurological sciences
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