0000000000269868

AUTHOR

Gaetano Bulfamante

showing 3 related works from this author

Posterior tibial tendon dysfunction: Clinical and magnetic resonance imaging findings having histology as reference standard.

2017

Abstract Objective To investigate the correlation between MRI, clinical tests, histopathologic features of posterior tibial tendon (PTT) dysfunction in patients with acquired adult flatfoot deformity surgically treated with medializing calcaneal osteotomy and flexor digitorum longus tendon transposition. Materials and methods Nineteen patients (11 females; age: 46 ± 15 year, range 18–75) were pre-operatively evaluated using the single heel rise (HR) and the first metatarsal rise (FMR) sign tests. Two reviewers graded the PTT tears on a I–III scale and measured the hindfoot valgus angle on the pre-operative MRI of the ankle. The specimens of the removed portion of PTT were histologically ana…

AdultMaleHistologyHeelAdolescentIntraclass correlationmedicine.medical_treatmentOsteotomyPreoperative care030218 nuclear medicine & medical imagingTendons03 medical and health sciencesYoung Adult0302 clinical medicineRetrospective StudiePreoperative CaremedicineHumansRadiology Nuclear Medicine and imagingPosterior Tibial Tendon DysfunctionTendonAgedRetrospective Studies030222 orthopedicsmedicine.diagnostic_testbusiness.industryFootMagnetic resonance imagingGeneral MedicineMiddle AgedReference Standardsmedicine.diseaseSingle heel riseFlatfootMagnetic Resonance ImagingOsteotomymedicine.anatomical_structureTendinopathyReference StandardFemaleHindfoot valguFirst metatarsal rise signTendinopathyAnklebusinessNuclear medicinePosterior Tibial Tendon DysfunctionHumanEuropean journal of radiology
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Second trimester uterine arteries pulsatility index is a function of placental pathology and provides insights on stillbirth aetiology: A multicenter…

2022

Introduction: The aim of this study was to investigate the relationships between maternal vascular malperfusions (MVM) and second trimester uterine arteries pulsatility index (UtA-PI) in cases of stillbirth (SB), compared to live-birth (LB) matched controls. Methods: This was a multicentre, observational, matched case-control study performed at five referral maternity centres over a 4-year period including SB and LB control pregnancies at high-risk for preeclampsia (PE) and/or fetal growth restriction (FGR), matched and stratified for UtA-PI MoM quartiles values of the SB cases. Logistic regression was used to assess the rates of each MVM finding, within each increasing MoM quartile subcate…

HematomaPulsatility indexPlacentaObstetrics and GynecologyLogistic regressionMaternal vascular malperfusionStillbirthUltrasonography PrenatalUterine artery Doppler velocimetryUterine ArteryReproductive MedicinePre-EclampsiaInfarctionPregnancyCase-Control StudiesPregnancy Trimester SecondPulsatile FlowHumansFemalePlacental histopathologyLogistic regression; Maternal vascular malperfusion; Placental histopathology; Pulsatility index; Stillbirth; Uterine artery Doppler velocimetryDevelopmental Biology
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Phosphodiesterase-5 Inhibition Alleviates Pulmonary Hypertension and Basal Lamina Thickening in Rats Challenged by Chronic Hypoxia

2018

javax.xml.bind.JAXBElement@6f8948ff Hypoxia represents both an outcome of cardiopulmonary diseases and a trigger for severe pulmonary complications as pulmonary hypertension. Because nitric oxide (NO) is a critical mediator in the development of pulmonary hypertension, the modulators of its downstream function may become target of pharmacological interventions aimed at alleviating the impact of this condition. Here, we investigate the effects of an early administration of phosphodiesterase-5 inhibitor in rats where pulmonary artery hypertension was induced by chronic exposure to hypoxia. javax.xml.bind.JAXBElement@162dc677 Rats were divided into three groups: normoxic control, hypoxic with …

0301 basic medicinemedicine.medical_specialtynitrites and nitratesPhysiologySildenafilsildenafil030204 cardiovascular system & hematologyphosphodiesterase 5lcsh:PhysiologyNitric oxideendothelial NO synthase; nitric oxide; nitrites and nitrates; phosphodiesterase 5; pulmonary hypertension; pulmonary vascular remodeling; right heart failure; sildenafil03 medical and health scienceschemistry.chemical_compound0302 clinical medicinenitric oxidePhysiology (medical)medicine.arteryInternal medicinepulmonary hypertensionmedicineendothelial NO synthaseOriginal ResearchCardiopulmonary diseaseLunglcsh:QP1-981business.industryright heart failureHypoxia (medical)medicine.diseasePulmonary hypertension030104 developmental biologymedicine.anatomical_structurechemistryVentriclePulmonary arteryCardiologymedicine.symptombusinesspulmonary vascular remodelingFrontiers in Physiology
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