Early exposure to paracetamol or to antibiotics and eczema at school age: Modification by asthma and rhinoconjunctivitis
The association between early exposure to paracetamol or to antibiotics and eczema is conflicting. This study aims to know whether the early exposure to those drugs is associated with eczema at school age, and whether the strength of the association is modified by the presence of asthma or rhinoconjunctivitis. Children aged 6-7 (n = 13908) from the International Study of Asthma and Allergies in Childhood in Spain provided data about current asthma, rhinoconjunctivitis and eczema. Parent-reported information was also obtained on paracetamol and antibiotic consumption during the first year of life. Logistic regression analysis with eczema as outcome and including exposure to paracetamol or to…
How the presence of rhinoconjunctivitis and the severity of asthma modify the relationship between obesity and asthma in children 67 years old
Summary Background The association between asthma and obesity in children, and the effect modification of allergy on this association have not been fully established. Aims The objective of the study was to know the effect modification of the severity of asthma and of the coexistence of rhinoconjunctivitis (RC) in the relationship between obesity and asthma. Methods A cross-sectional study of 17145 schoolchildren 6‐7 years old from eight Spanish cities who had completed information on height and weight of the ISAAC phase III questionnaire, which also included questions about asthma and RC symptoms and on various risk factors. Body mass index (BMI) was used to define obesity according to inte…
Evolución temporal de la prevalencia de síntomas de rinitis alérgica en escolares de 13-14 años de 8 áreas españolas entre 1993-1994 y 2001-2002 según el Estudio Internacional sobre Asma y Alergias en la Infancia (ISAAC)
Fundamento y objetivo Estimar la evolucion temporal de la prevalencia de sintomas de rinitis alergica y sus variaciones geograficas. Pacientes y metodo Durante 2001-2002 se efectuo la tercera fase del estudio ISAAC, cuyos resultados se compararon con los de la primera fase (1993-1994). Este estudio transversal incluyo a 30.046 escolares de 13-14 anos en 9 centros (Asturias, Barcelona, Bilbao, Cartagena, Castellon, Madrid, Pamplona, Valencia y Valladolid). Se empleo un cuestionario sobre sintomas de rinitis cumplimentado por los escolares en colegios e institutos con una participacion entre el 100 y el 75,8%. Se emplearon modelos de regresion de Poisson para estudiar la evolucion. Resultados…
Contaminación del aire y síntomas recientes de asma, rinitis alérgica y eccema atópico en escolares de 6 y 7 años
Resumen Introduccion El objetivo del estudio ha sido analizar la relacion entre contaminantes del aire y la prevalencia de sintomas recientes de asma, rinitis alergica y eccema atopico, en escolares de 6 y 7 anos. Pacientes y metodos La prevalencia de sintomas de enfermedades alergicas recientes (ultimos 12 meses) se obtuvo mediante el cuestionario del estudio ISAAC (International Study of Asthma and Allergies in Childhood) Espana, con la participacion de 7 centros (Asturias, Barcelona, Bilbao, Cartagena, La Coruna, Madrid y Valencia) y 20.455 escolares de 6 y 7 anos, durante 2002–2003. De los sistemas de deteccion de contaminantes de los centros citados se obtuvieron datos de las concentra…