0000000000276587

AUTHOR

Angelo Farzati

showing 2 related works from this author

Long-term effects of oral and transdermal hormone replacement therapy on plasma homocysteine levels.

2003

Objective To compare the long-term effects of oral and transdermal hormone replacement therapy (HRT) on serum homocysteine levels in postmenopausal women. Design An open, prospective, controlled study. Seventy-five healthy postmenopausal women were recruited as eligible for the study. Fifty women seeking HRT were randomized to receive continuous 17beta-estradiol, either by oral (2 mg daily; n = 25) or transdermal (50 microg daily; n = 25) administration, plus 10 mg dydrogesterone daily for 14 days of each 28-day cycle. Twenty-five women unwilling to receive hormone treatment received only calcium supplementation, representing the control group. Fasting blood samples were analyzed at baselin…

Oralmedicine.medical_specialtyAdministration CutaneouHomocysteineEstronemedicine.medical_treatmentHRTAdministration OralEstroneDydrogesteroneAdministration CutaneousGastroenterologylaw.inventionchemistry.chemical_compoundFollicle-stimulating hormoneRandomized controlled triallawReference ValuesInternal medicineMedicineHumansReference ValueProspective StudiesProspective cohort studyHomocysteineTransdermalEstradiolProgesterone Congenersbusiness.industryEstrogen Replacement TherapyObstetrics and GynecologyHormone replacement therapy (menopause)Progesterone CongenerMiddle AgedHomocysteine; HRT; TransdermalPostmenopauseProspective StudieEndocrinologychemistryDydrogesteroneDrug Therapy CombinationFemaleFollicle Stimulating HormonebusinessTransdermalmedicine.drugHumanMenopause (New York, N.Y.)
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Effects of transdermal hormone replacement therapy on levels of soluble P- and E-selectin in postmenopausal healthy women

2002

Abstract Objective: To study the adhesion molecule pattern in postmenopausal women who were not receiving hormone replacement therapy (HRT), HRT users, and fertile women. Design: Case-control study. Setting: Second University of Naples, Naples, Italy. Patient(s): Fifty healthy naturally postmenopausal women and 20 fertile women. Intervention(s): Twenty-six women received no HRT and 24 received continuous transdermal 17β−estradiol, 0.05 mg/d, plus oral acetate nomegestrol, 5 mg/d. Main Outcome Measure(s): Levels of the soluble forms of intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), E-selectin, and P-selectin. Result(s): Women who did not received HRT …

Nomegestrolmedicine.medical_specialtyAdministration Cutaneougenetic structuresP-selectinmedicine.drug_classHormone Replacement Therapymedicine.medical_treatmentHRTVascular Cell Adhesion Molecule-1Administration Cutaneouschemistry.chemical_compoundInternal medicineE-selectinmedicineHumansICAM-1biologyEstradiolbusiness.industryCase-control studyObstetrics and GynecologyHormone replacement therapy (menopause)Megestrolmedicine.diseaseIntercellular Adhesion Molecule-1AtherosclerosisMenopausePostmenopauseP-SelectinEndocrinologyReproductive MedicinechemistryEstrogenCase-Control Studiesbiology.proteinAdhesion molecules; Atherosclerosis; HRTFemalebusinessCase-Control StudieE-SelectinAdhesion moleculesHuman
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