0000000000277101

AUTHOR

Eadc-adni Working Group On The Harmonized Protocol For Manual Hippocampal Segmentation And

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Training labels for hippocampal segmentation based on the EADC-ADNI harmonized hippocampal protocol

2015

Abstract Background The European Alzheimer's Disease Consortium and Alzheimer's Disease Neuroimaging Initiative (ADNI) Harmonized Protocol (HarP) is a Delphi definition of manual hippocampal segmentation from magnetic resonance imaging (MRI) that can be used as the standard of truth to train new tracers, and to validate automated segmentation algorithms. Training requires large and representative data sets of segmented hippocampi. This work aims to produce a set of HarP labels for the proper training and certification of tracers and algorithms. Methods Sixty-eight 1.5 T and 67 3 T volumetric structural ADNI scans from different subjects, balanced by age, medial temporal atrophy, and scanner…

MaleEpidemiologyIntraclass correlationpathology [Cognitive Dysfunction]methods [Pattern Recognition Automated]Hippocampal formationHippocampusFunctional LateralityPattern Recognition Automatedpathology [Alzheimer Disease]ddc:616.89methods [Magnetic Resonance Imaging]methods [Image Processing Computer-Assisted]Image Processing Computer-AssistedSegmentationHARPAged 80 and overmedicine.diagnostic_testHealth PolicyOrgan SizeMiddle AgedMagnetic Resonance Imaginginstrumentation [Magnetic Resonance Imaging]Temporal LobePsychiatry and Mental healthFemalePsychologymethods [Neuroimaging]Algorithmsmethods [Imaging Three-Dimensional]anatomy & histology [Hippocampus]educationNeuroimagingTemporal lobeCellular and Molecular NeuroscienceImaging Three-DimensionalDevelopmental NeuroscienceNeuroimagingAlzheimer DiseasemedicineHumansCognitive Dysfunctionddc:610AgedProtocol (science)business.industryReproducibility of ResultsMagnetic resonance imagingpathology [Temporal Lobe]pathology [Hippocampus]Neurology (clinical)Geriatrics and GerontologyAtrophyNuclear medicinebusinessNeuroscience
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