0000000000278079

AUTHOR

Lars-olof Hattenbach

showing 6 related works from this author

Factors predicting normal visual acuity following anatomically successful macular hole surgery

2021

Purpose: To assess the incidence of normal vision following anatomically successful macular hole surgery and associated clinical variables. Methods: Multicentre, retrospective chart review. Preoperative, intraoperative and postoperative clinical data were extracted from electronic medical records from seven European vitreoretinal units. Inclusion criteria were as follows: eyes undergoing primary vitrectomy for idiopathic full-thickness macular hole from January 2015 to January 2018; postoperative macular hole closure confirmed by spectral domain optical coherence tomography (OCT); preoperative pseudophakia or phakic eyes receiving combined cataract surgery; one-year follow-up. The primary o…

Malemedicine.medical_specialtyMultivariate analysisVisual acuitygenetic structuresPseudophakiamacular hole closuremedicine.medical_treatmentVisual AcuityvitrectomyVitrectomyTime-to-Treatment03 medical and health sciences0302 clinical medicinefull-thickness macular hole; idiopathic macular hole; macular hole closure; macular hole surgery; vitrectomymedicineFull-thickness macular holeHumansMacular holeAgedRetrospective Studiesfull-thickness macular holeidiopathic macular holebusiness.industryGeneral MedicineOdds ratioCataract surgeryMiddle Agedmedicine.diseaseRetinal Perforationseye diseasesConfidence intervalSurgeryOphthalmologyTreatment Outcomemacular hole surgery030221 ophthalmology & optometryFemalesense organsmedicine.symptombusiness030217 neurology & neurosurgeryTomography Optical CoherenceFollow-Up Studies
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Incidence of posterior vitreous detachment after cataract surgery

2009

Purpose To report the incidence of posterior vitreous detachment (PVD) after uneventful state-of-the-art small-incision phacoemulsification with implantation of a posterior chamber intraocular lens (PC IOL). Setting Department of Ophthalmology, Ludwigshafen Hospital, Ludwigshafen, Germany. Methods This prospective study evaluated the vitreous status of eyes by biomicroscopic examination, indirect binocular ophthalmoscopy, and B-scan ultrasonography before planned cataract surgery. Patients with the posterior vitreous attached were included for follow-up and examined 1 week, 1 month, and 1 year after uneventful phacoemulsification with PC IOL implantation. The preoperative prevalence and pos…

AdultMaleMicrosurgerymedicine.medical_specialtygenetic structuresEye diseasemedicine.medical_treatmentVitreous DetachmentPosterior vitreous detachmentOphthalmoscopyPostoperative ComplicationsLens Implantation IntraocularGermanyOphthalmologymedicineHumansProspective StudiesDioptreAgedUltrasonographyAged 80 and overPhacoemulsificationmedicine.diagnostic_testbusiness.industryIncidencePhacoemulsificationMiddle AgedMicrosurgeryCataract surgerymedicine.diseaseeye diseasesSensory SystemsSurgeryVitreous DetachmentOphthalmologyFemaleSurgerysense organsbusinessJournal of Cataract and Refractive Surgery
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Experimental Percutaneous Cannulation of the Supraorbital Arteries: Implication for Future Therapy

2005

Purpose There is some evidence to suggest that thrombolysis has a beneficial effect in retinal vessel occlusion. However, there is concern that this therapeutic approach carries the risk of hemorrhage. Retrograde cannulation of the supraorbital arteries followed by irrigation with fibrinolytic agents may have the potential to minimize the risk of major complications. The study was conducted to investigate the anatomic and sonographic features of the supraorbital arteries. Methods This cadaver dissection study was performed on the orbits of 12 cadaveric specimens. In each orbit, the supraorbital region was dissected, followed by cannulation of the supraorbital vessels and injection of ink. I…

AdultMalePercutaneousSupratrochlear arteryDissection (medical)Ophthalmic ArteryCadavermedicine.arteryCatheterization PeripheralRetinal Vein OcclusionOcclusionmedicineHumansThrombolytic Therapybusiness.industryUltrasonography DopplerArteriesAnatomySupraorbital arterymedicine.diseaseCarbonmedicine.anatomical_structureFemalebusinessOrbitFibrinolytic agentOrbit (anatomy)Investigative Opthalmology & Visual Science
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Switching to intravitreal fluocinolone acetonide implant for refractory diabetic macular edema: 12- and 24-month results

2021

Purpose: To report visual and anatomical outcomes of chronic/refractory diabetic macular edema (DME) treated with intravitreal fluocinolone acetonide implant. Setting: Retrospective, one arm, multicentric study. Method: Between 2013 and 2018, 27 consecutive eyes of 25 patients with chronic/refractory DME were treated with a fluocinolone acetonide intravitreal implant. Best registered visual acuity (BRVA), central retinal thickness (CRT), and Goldmann tonometry intraocular pressure (IOP) were assessed at 12 and 24 months. The need for IOP lowering treatment as well as top-up therapy during the follow-up were also assessed. Results: The duration of DME prior to treatment in our study was 54 ±…

0301 basic medicinemedicine.medical_specialtygenetic structuresDiabetic macular edemaMacular EdemaRetina03 medical and health sciences0302 clinical medicineRefractoryFluocinolone acetonideOphthalmologyDiabetes MellitusHumansMedicineGlucocorticoidsRetrospective StudiesDrug ImplantsDiabetic Retinopathybusiness.industryGeneral Medicineeye diseasesOphthalmology030104 developmental biologyFluocinolone AcetonideIntravitreal Injections030221 ophthalmology & optometryImplantbusinessmedicine.drugEuropean Journal of Ophthalmology
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Ranibizumab for Branch Retinal Vein Occlusion Associated Macular Edema Study (RABAMES): six-month results of a prospective randomized clinical trial

2014

Purpose To compare standard-of-care grid laser photocoagulation versus intravitreal ranibizumab (IVR) versus a combination of both in the treatment of chronic (>3 months) macular oedema secondary to branch retinal vein occlusion. Methods Prospective, randomized, multicentre clinical trial. Thirty patients with a best-corrected visual acuity (BCVA) between 20/320 and 20/40 were randomized 1:1:1 to receive grid laser or three monthly injections of 0.5 mg IVR or both followed by 3 months of observation. Results Mean change from baseline BCVA at month 6 was +2 letters [laser; 0.04 logMAR, 95% confidence interval (−0.17; 0.25)], +17 letters [IVR; 0.34 (0.19; 0.5)] and +6 letters [combination; 0.…

AdultMaleVascular Endothelial Growth Factor Amedicine.medical_specialtyVisual acuitygenetic structuresVisual AcuityAngiogenesis InhibitorsAntibodies Monoclonal HumanizedMacular Edemalaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicineRandomized controlled trialRecurrencelawRanibizumabOphthalmologyRetinal Vein OcclusionHumansMedicineProspective Studies030212 general & internal medicineMacular edemaAgedAged 80 and overLaser Coagulationbusiness.industryRetinalGeneral MedicineMiddle Agedmedicine.diseaseCombined Modality TherapyConfidence interval3. Good healthSurgeryClinical trialOphthalmologychemistryIntravitreal Injections030221 ophthalmology & optometryBranch retinal vein occlusionFemaleLasers SemiconductorRanibizumabmedicine.symptombusinessmedicine.drugActa Ophthalmologica
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Course of intraocular pressure after intravitreal injection of 0.05 mL ranibizumab (Lucentis).

2009

Purpose This prospective study examines the changes in short-term intraocular pressure (IOP) in patients with wet age-related macular degeneration (AMD) receiving intravitreal injections of 0.05 mL ranibizumab (Lucentis®) in a supine position. Methods A total of 45 eyes (45 patients, 16 M, 29 F, mean age: 78 y) received intravitreal ranibizumab injections for treatment of wet AMD (0.05 mL = 0.5 mg). The IOP was measured by Schiötz tonometry immediately preoperatively and postoperatively, and also after 3 and 10 minutes in a supine position. No history of glaucoma was present. Results The mean preoperative IOP was 22.4±5.5 mmHg in supine position. Immediately after the injection, IOP increas…

MaleVascular Endothelial Growth Factor AIntraocular pressuremedicine.medical_specialtySupine positiongenetic structuresAngiogenesis InhibitorsAntibodies Monoclonal HumanizedInjections03 medical and health sciencesTonometry Ocular0302 clinical medicineOphthalmologyRanibizumabWet age-related macular degenerationmedicineSupine PositionHumansIn patientProspective StudiesProspective cohort studyIntraocular PressureAgedAged 80 and overbusiness.industryAntibodies MonoclonalGeneral MedicineMacular degenerationMiddle Agedmedicine.diseaseeye diseasesVitreous BodyOphthalmology030221 ophthalmology & optometryWet Macular DegenerationFemalesense organsRanibizumabbusiness030217 neurology & neurosurgerymedicine.drugEuropean journal of ophthalmology
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