0000000000278271

AUTHOR

Johanna Lepeule

0000-0001-8907-197x

showing 3 related works from this author

Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth.

2021

We would like to thank all the families that participated in these studies for their generous contribution. Detailed acknowledgements and funding can be found in Sup plementary Material.

EpigenomicsMaternal smokingPlacentaGeneral Physics and AstronomyReproductive health and childbirthBioinformaticsLow Birth Weight and Health of the NewbornEpigenesis GeneticFetal DevelopmentPregnancyInfant MortalityFetal growth2.1 Biological and endogenous factorsAetiologyPediatricMultidisciplinaryQSmokingCord bloodDNA methylationEpigeneticsFemalemedicine.symptomScience1.1 Normal biological development and functioningInflammationFetus -- Trastorns del creixementBiologyGeneral Biochemistry Genetics and Molecular BiologyArticleGenetic HeterogeneityGeneticPretermUnderpinning researchTobaccomedicineGeneticsHumansEpigeneticsConditions Affecting the Embryonic and Fetal PeriodsNucleotide MotifsPregnancyHormone activitydNaMGeneral ChemistryEpigenomeDNA MethylationPerinatal Period - Conditions Originating in Perinatal Periodmedicine.diseaseEmbarassades -- Consum de tabacGood Health and Well BeingRisk factorsEpigenesis
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Urban environment and cognitive and motor function in children from four European birth cohorts

2021

[EN]Background: The urban environment may influence neurodevelopment from conception onwards, but there is no evaluation of the impact of multiple groups of exposures simultaneously. We investigated the association between early-life urban environment and cognitive and motor function in children. Methods: We used data from 5403 mother-child pairs from four population-based birth-cohorts (UK, France, Spain, and Greece). We estimated thirteen urban home exposures during pregnancy and childhood, including: built environment, natural spaces, and air pollution. Verbal, non-verbal, gross motor, and fine motor functions were assessed using validated tests at five years old. We ran adjusted multi-e…

Urban environment010501 environmental sciences01 natural sciences0302 clinical medicineCognitionPregnancyCognició en els infants11. SustainabilityGE1-350030212 general & internal medicineChildrenMotor skillComputingMilieux_MISCELLANEOUSDesenvolupament urbàGeneral Environmental ScienceSDG 15 - Life on Land2. Zero hungereducation.field_of_studyAir Pollutants4. Educationmotor functionCohortCognitioncohortSDG 11 - Sustainable Cities and Communities3. Good healthChild PreschoolCohortBirth CohortFemaleCognitive functionPsychologyPopulationGross motor skill03 medical and health scienceschildrenUrban planningAir PollutionmedicineHumanseducationMotor functioncognitive function0105 earth and related environmental sciencesPregnancyEnvironmental Exposuremedicine.diseaseurban environmentConfidence intervalEnvironmental sciencesSpain[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieParticulate Matter[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieDemography
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The Urban Exposome during Pregnancy and Its Socioeconomic Determinants

2018

Background: The urban exposome is the set of environmental factors that are experienced in the outdoor urban environment and that may influence child development. Objective: The authors’ goal was to describe the urban exposome among European pregnant women and understand its socioeconomic determinants. Methods: Using geographic information systems, remote sensing and spatio-temporal modeling we estimated exposure during pregnancy to 28 environmental indicators in almost 30,000 women from six population-based birth cohorts, in nine urban areas from across Europe. Exposures included meteorological factors, air pollutants, traffic noise, traffic indicators, natural space, the built environment…

[SDE] Environmental SciencesUrban PopulationHealth Toxicology and Mutagenesis05 Environmental SciencesNEIGHBORHOOD WALKABILITY010501 environmental sciencesToxicology01 natural sciences0302 clinical medicineUSE REGRESSION-MODELS11. Sustainability030212 general & internal medicineNITROGEN-DIOXIDE11 Medical And Health Sciences3. Good healthPeer reviewEuropeMESH: Urban PopulationGeographyGREEN SPACESMESH: Environmental PollutantsMESH: Young Adult[SDE]Environmental SciencesENVIRONMENTAL JUSTICEEnvironmental PollutantsFemaleAdultExposomemedicine.medical_specialtyMESH: Socioeconomic FactorsAdolescentMESH: Environmental ExposureYoung Adult03 medical and health sciencesEnvironmental healthmedicineMESH: CitiesHumansCitiesSocioeconomic status0105 earth and related environmental sciencesEnvironmental justiceMESH: AdolescentPregnancyMESH: HumansLand useLAND-USEResearchPublic healthPublic Health Environmental and Occupational HealthMESH: AdultEnvironmental Exposuremedicine.diseaseChild developmentAMBIENT AIR-POLLUTIONROAD TRAFFIC NOISERESIDENTIAL EXPOSURESocioeconomic Factors[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie13. Climate actionCOHORT PROFILE[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieMESH: EuropeMESH: Female
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