0000000000280379
AUTHOR
M. Tripi
L'aztreonam Nelle Infezioni Delle Vie Urinarie
L'etoposide per via Intravescicale Nella Chemioprofilassi Degli Uroteliomi Superficiali Della Vescica
Infezioni Delle Vie Urinarie: Germi responsabili e chemioresistenza negli anni 1978–1983
Infezioni e flogosi delle vie urinarie nella donna
Randomized Comparative Trial with Ceftizoxime and Cefotaxime in Urinary Tract Infections
Ceftizoxime, a new, semisynthetic, beta-lactamase-resistant cephalosporin, is not metabolized in man and is excreted almost entirely as the original active compound in the urine. The efficacy and safety of ceftizoxime were assessed in 80 patients with acute and chronic urinary infections, with and without associated pathological conditions, in comparison with cefotaxime. Two dosage schedules, 1 g or 0.5 g every 12 h, i.v. or i.m. for 10 days, were adopted according to the severity of each case and to separate randomization tables for each schedule; causal agents were all sensitive to both drugs in vitro. The overall results were excellent. Safety was excellent in almost all cases. In this t…