0000000000281867

AUTHOR

Martyna Fronczek

0000-0003-3669-1416

showing 5 related works from this author

Early and Longitudinal Humoral Response to the SARS-CoV-2 mRNA BNT162b2 Vaccine in Healthcare Workers: Significance of BMI, Adipose Tissue and Muscle…

2022

Background: This study aimed to investigate the early and longitudinal humoral response in Healthcare Workers (HCWs) after two doses of the BNT162b2 vaccine and to assess the association between metabolic and anthropometric parameters and the humoral response after vaccination. Methods: The study included 243 fully vaccinated HCWs: 25.50% previously infected with SARS-CoV-2 (with prior history of COVID-19—PH) and 74.40%—uninfected, seronegative before the first vaccination (with no prior history of COVID-19—NPH). IgG antibodies were measured, and sera were collected: prior to the vaccination, 21 days after the first dose, and 14 days and 8 months after the second dose. Res…

VaccinesCOVID-19 VaccinesSARS-CoV-2Health PersonnelMusclesCOVID-19Body Mass IndexInfectious DiseasesAdipose TissueMuscular DiseasesVirologyHumansIgG antibody; SARS-CoV-2; COVID-19; healthcare workers; health care professionals; COVID-19 vaccine; BNT162 vaccine; adipose tissue; body composition; immunizationRNA MessengerBNT162 VaccineViruses-Basel
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High progesterone levels are associated with family history of premature coronary artery disease in young healthy adult men.

2019

Background & aimsThe offspring of patients with premature coronary artery disease (P-CAD) are at higher risk for cardiovascular disease, compared with subjects without a family history (FH) of P-CAD. The increased risk for cardiovascular disease in subjects with FH of early-onset CAD results from unfavorable genetic variants as well as social, behavioral and environmental factors, which are more prevalent in this group. Previous studies have shown that specific sex hormone levels may be associated with the risk of cardiovascular disease. The aim of this study was to compare wide range of biochemical marker levels including i.e. the levels of luteinizing hormone (LH), follicle-stimulating ho…

AdultMaleAdolescentOffspringSciencePhysiology030209 endocrinology & metabolismCoronary Artery Disease030204 cardiovascular system & hematologyBody Mass Index03 medical and health sciencesYoung Adult0302 clinical medicineSex hormone-binding globulinRisk FactorsMedicineHumansYoung adultFamily historyTestosteroneProgesteroneMultidisciplinarybiologybusiness.industryQCholesterol HDLSmokingCase-control studyRCholesterol LDLCase-Control Studiesbiology.proteinMedicineFemaleLuteinizing hormonebusinessBody mass indexPloS one
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The Antibody Response to the BNT162b2 mRNA COVID-19 Booster in Healthcare Workers: Association between the IgG Antibody Titers and Anthropometric and…

2022

Background: Research shows that in most people, two-dose vaccination helps to shape the humoral response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Further studies are required to learn about the vaccine’s effectiveness after boosting. Methods: We conducted a prospective study among 103 healthcare workers (HCWs) from a regional multi-specialty hospital vaccinated with three doses of the BNT162b2 vaccine. We compared their immunoglobulin G (IgG) titers 14 days after the second dose with those 21 days after the booster. We also compared their anthropometric and body composition parameters with IgG concentrations at the same time points. Results: Twenty-one days aft…

PharmacologyInfectious DiseasesDrug DiscoveryImmunologyPharmacology (medical)IgG antibody; SARS-CoV-2; COVID-19; healthcare workers; humoral response; COVID-19 vaccine; BNT162b2 vaccine; immunization; body composition; boosterVaccines; Volume 10; Issue 10; Pages: 1638
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Family History of Premature Coronary Artery Disease (P-CAD)—A Non-Modifiable Risk Factor? Dietary Patterns of Young Healthy Offspring of P-CAD Patien…

2018

Dietary habits of healthy offspring with a positive family history of premature coronary artery disease (P-CAD) have not been studied so far. The aim of this study was twofold: (1) to identify dietary patterns in a sample of young healthy adults with (cases) and without (controls) family history of P-CAD, and (2) to study the association between dietary patterns and family history of P-CAD. The data came from the MAGNETIC case-control study. The participants were healthy adults aged 18&ndash

Male0301 basic medicineEpidemiologyCoronary Artery Disease030204 cardiovascular system & hematologyLogistic regression0302 clinical medicineRisk FactorsOdds RatioMedicineFamily historypremature coronary artery diseasefamily historyPCANutrition and DieteticsPremature coronary artery diseaseP-CADFemalelcsh:Nutrition. Foods and food supplyAdultAdolescentOffspringdietary patternslcsh:TX341-641Diet SurveysModels BiologicalArticleYoung Adult03 medical and health sciencesSex FactorsHumansFamilyRisk factorExercise030109 nutrition & dieteticsbusiness.industryCase-control studyFeeding BehaviorOdds ratioConfidence intervalDietCross-Sectional StudiesLogistic ModelsSocioeconomic FactorsP-CACase-Control StudiesFFQ-6businessFood ScienceDemographyNutrients
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SARS-CoV-2 Antibody Screening in Healthcare Workers in Non-Infectious Hospitals in Two Different Regions of Southern Poland (Upper Silesia and Opole …

2021

(1) Background: Detection of asymptomatic or subclinical human coronavirus SARS-CoV-2 infection in healthcare workers (HCWs) is crucial for understanding the overall prevalence of the new coronavirus and its infection potential in public (non-infectious) healthcare units with emergency wards. (2) Methods: We evaluated the host serologic responses, measured with semi-quantitative ELISA tests (IgA, IgG, IgM abs) in sera of 90 individuals in Hospital no. 4 in Bytom, 84 HCWs in the University Hospital in Opole and 25 in a Miasteczko Śląskie local surgery. All volunteers had negative RT-PCR test results or had not had the RT-PCR test performed within 30 days before sampling. The ELISA test was m…

SARS-CoV-2; COVID-19; RT-PCR; asymptomatic; health-care professionals; serological surveillance; antibody screening; immunoglobulinsmedicine.medical_specialtyHealth PersonnelHealth Toxicology and MutagenesisSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)serological surveillanceimmunoglobulinsRT-PCRAsymptomaticArticleantibody screeningSerology03 medical and health sciences0302 clinical medicineInternal medicineHealth caremedicineHumansasymptomaticProspective Studies030212 general & internal medicineProspective cohort study030304 developmental biologySubclinical infection0303 health scienceshealth-care professionalsbusiness.industrySARS-CoV-2Public Health Environmental and Occupational HealthRCOVID-19virus diseasesMedicinePolandmedicine.symptombusinessNon infectiousAntibody screeningInternational Journal of Environmental Research and Public Health; Volume 18; Issue 8; Pages: 4376
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