Lacrimal glands herniation in patients with Graves’ Ophthalmopathy: an effective MRI-derived marker of disease activity

Aims and objectives Methods and materials Results Conclusion Personal information References

SEMEIOTICA NEURORADIOLOGICA E POSSIBILI DIAGNOSI DIFFERENZIALI DI UN RARO CASO DI MIELOLIPOMA PRESACRALE

SCOPO Presentiamo il caso di una paziente anziana (74aa) con tipica sintomatologia da artrosi e discopatia lombo-sacrale (rigidità e dolore alla regione lombare con tipica irradiazione ai glutei ed alla superficie posteriore di entrambi gli arti inferiori, con associata sensazione di intorpidimento) e segni di radicolopatia L4-L5-S1 all’esame obiettivo neurologico, che si presenta alla nostra attenzione per eseguire un esame RM del rachide lombo-sacrale. MATERIALI E METODI L’esame RM è stato eseguito in condizioni di base con sequenze TSE-T1, TSE-T2 e STIR-T2 secondo piani sagittali ed assiali (GE Signa HDxt 1,5T). E’ stata inoltre effettuata un’integrazione RM dopo somministrazione di md…

A CASE OF A PRESACRAL MYELOLIPOMA: IMAGING FINDINGS AND DIFFERENTIAL DIAGNOSIS CHECKLIST OF OTHER PRESACRAL MASSES

PURPOSE: There have been many reports describing adrenal myelolipoma but there have been only few reports of extraadrenal myelolipoma. We describe a case of an elderly woman with lower back pain due to age-related spondyloarthrosis and mild discopathy with a presacral myelolipoma as incidental finding. We also discuss about common and uncommon imaging findings of other presacral masses. METHODS: A 74 years-old woman came to our observation to perform an MRI of the lumbar spine for typical lumbar back pain. MR imaging revealed, in addition to the signs of mild scoliosis and spondylo-disc-arthrosis, a presacral mass showing heterogeneously high signal in all sequences and almost completely su…

CONTRIBUTO DELLA RM PERFUSIONALE IN ASSOCIAZIONE ALLA SPETTROSCOPIA RM SINGLE VOXEL NELLA DEFINIZIONE DEL GRADING DEI GLIOMI CEREBRALI.

Diagnostic Value of Prenatal MR Imaging in the Detection of Brain Malformations in Fetuses before the 26th Week of Gestational Age.

BACKGROUND AND PURPOSE: In several countries, laws and regulations allow abortion for medical reasons within 24–25 weeks of gestational age. We investigated the diagnostic value of prenatal MR imaging for brain malformations within 25 weeks of gestational age. MATERIALS AND METHODS: We retrospectively included fetuses within 25 weeks of gestational age who had undergone both prenatal and postnatal MR imaging of the brain between 2002 and 2014. Two senior pediatric neuroradiologists evaluated prenatal MR imaging examinations blinded to postnatal MR imaging findings. With postnatal MR imaging used as the reference standard, we calculated the sensitivity, specificity, positive predictive value…

Lacrimal gland herniation in Graves ophthalmopathy: a simple and useful MRI biomarker of disease activity

Lacrimal gland (LG) involvement in patients with Graves ophthalmopathy (GO) has been considered as a potential cause of the associated GO symptoms and different studies demonstrated the LG involvement in patients with GO than healthy controls. The aim of this study was to evaluate LG involvement, through measurement of its herniation, using a magnetic resonance imaging (MRI) index, in patients with different GO activities. Thirty-two consecutive Caucasian patients affected by GO were enrolled and grouped in group A (16 with inactive GO, CAS < 3) and B (16 with active GO, CAS ≥ 3) according to their GO activity. All patients underwent clinical-endocrinological assessment, a complete ocular e…

Presacral Myelolipoma

Many reports have described adrenal myelolipomas but there have been only a few reports of extra-adrenal myelolipomas. We describe a 74-year-old woman who came to our observation for MRI of the lumbar spine for typical lumbar back pain. In addition to signs of mild scoliosis and spondylo disc arthrosis, MR imaging revealed a presacral mass showing a heterogeneously high signal in all pulse sequences and almost completely suppressed on inversion recovery sequences for fat tissue. CT imaging confirmed the fatty nature of the lesion and no signs of bone involvement. These findings were most consistent with a diagnosis of a rare presacral myelolipoma as confirmed at histopathologic analysis. T…

ASSESSMENT OF BRAIN METASTASES VOLUME CONTROL DURING STEREOTACTIC RADIOSURGERY BY LONGITUDINAL REGION GROWTH MR IMAGE SEGMENTATION ANALYSIS