0000000000284076
AUTHOR
A Calabrese
Il ruolo dell’infiammazione nella prognosi del recupero funzionale dei pazienti in assistenza domiciliare integrata
This study has correlated the functional recovery achieved by patients treated in integrated home care following a stroke or a fracture with biochemical parameters, lipid profile and nutritional status. The study involved 51 patients (average age 79.5 years) who were receiving home rehabilitation treatment. A statistically significant association between functional improvement and lower levels of fibrinogen, PCR, LDL-cholesterol and BUN emerged. The study supports the need for further investigation on the predictive role of inflammatory markers.
Oxidative stress and antioxidant status in beta-thalassemia major: iron overload and depletion of lipid-soluble antioxidants
Because of continuous blood transfusions, thalassemia patients are subjected to peroxidative tissue injury by the secondary iron overload. In accordance, analysis of serum from 42 beta-thalassemia patients, aged 4 to 40 years, showed that the mean concentrations of conjugated diene lipid hydroperoxides (CD), lipoperoxides evaluated as malondialdehyde/ thiobarbituric acid (MDA/TBA) adducts, and protein carbonyls increased about twofold with respect to control. Ferritin levels were positively correlated with the amount of MDA (r = .41; P = .007) and showed a positive trend with CD (r = .31; P = .07) and protein carbonyls (r = .35; P = .054), as further evidence of the deleterious effects of h…